Multidimensional Atomic Force Microscopy: A Versatile Novel Technology for Nanopharmacology Research
Journal Title: The AAPS Journal - Year 2010, Vol 12, Issue 4
Abstract
The online version of this article (doi:10.1208/s12248-010-9232-y) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Ratnesh Lal, Srinivasan Ramachandran, Morton F. Arnsdorf
Keywords
Related Articles
- EP ID EP681435
- DOI 10.1208/s12248-010-9232-y
- Views 85
- Downloads 0
How to Regulate Nonbiological Complex Drugs (NBCD) and Their Follow-on Versions: Points to Consider
The aim of this critical review is to reach a global consensus regarding the introduction of follow-on versions of nonbiological complex drugs (NBCD). A nonbiological complex drug is a medicinal product, not being a biol...
Renal Organic Anion Transporters (SLC22 Family): Expression, Regulation, Roles in Toxicity, and Impact on Injury and Disease
Organic solute flux across the basolateral and apical membranes of renal proximal tubule cells is a key process for maintaining systemic homeostasis. It represents an important route for the elimination of metabolic wast...
Recent Advances in Structure-Based Virtual Screening of G-Protein Coupled Receptors
In addition to the rhodopsin crystal structure, high-resolution crystal structures of ligand-mediated G-protein-coupled receptors (GPCRs) have recently become available, and these have become attractive templates for dev...
FDA Critical Path Initiatives: Opportunities for Generic Drug Development
FDA’s critical path initiative documents have focused on the challenges involved in the development of new drugs. Some of the focus areas identified apply equally to the production of generic drugs. However, ther...
Recognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transporters
The plasma membrane monoamine transporters terminate neurotransmission by removing dopamine, norepinephrine, or serotonin from the synaptic cleft between neurons. Specific inhibitors for these transporters, including the...