Multiple Myeloma Presenting as Respiratory Stridor
Journal Title: Iranian Journal of Blood and Cancer - Year 2017, Vol 9, Issue 2
Abstract
Extramedullary plasmacytoma occurs in 18% of patients with multiple myeloma. Laryngeal involvement in multiple myeloma is rare, and only a few cases have been reported. We present a case of a 44-year-old women with multiple myeloma who presented with stridor due to a mass involving the larynx which was initially proven to be plasmacytoma on biopsy. She had evidence of multiple myeloma of IgA lambda subtype. She was treated with bortezomib containing chemotherapy followed by lenalidomide as maintenance therapy. She attained complete remission and is alive in remission at 3 years of treatment.
Authors and Affiliations
Geetha Narayanan, Varun Rajan, T. R Preethy, Lali V Soman
Main Determinants of Severe Neutropenia in Patients with Solid Tumors Receiving Adjuvant Chemotherapy
Background:Chemotherapy-induced neutropenia as a major toxicity of systemic chemotherapy is commonly associated with substantial mortality and morbidity, and thus identifying its determinants is necessary. This study was...
Haemovigilance in Iran (First Report)
Haemovigilance is a system with standard program to cover the entire transfusion chain, monitor, evaluate and analyse the data to improve patients’ safety. We report the implemented haemovigilance system in hospitals an...
Density of Platelet GPIIb-IIIa and Bleeding Severity in Iranian Patients with Glanzmann’s Thrombasthenia
Background: Glanzmann’s Thrombasthenia (GT) is a rare autosomal, recessive, bleeding syndrome. The main aim of this study was to investigate the relationship between symptoms, bleeding severity, and gender and subtypes o...
Molecular Markers in Neuroblastoma
Neuroblastoma, one of the common malignant childhood tumors, arises from neuroblast cells derived from the neural crest and destined for the adrenal medulla and the sympathetic nervous system and shows remar...
Microparticle Formation and Platelet Shrinkage in Type-I Glanzmman Thrombasthenia Platelets
Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apopto...