Multiple primary malignant neoplasms in a nonagenarian : Case report and review of literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Multiple primary malignant neoplasms are uncommon, but the incidence is increasing owing to increased long term survival amongst cancer patients, longer life expectancy and better diagnostic techniques. They may be metachronous (i.e. occurrence 6 months or more after detection of primary malignancy) or synchronous (occurrence within 6 months of detection of primary malignancy). Here, we present a case of a 94 year old male, diagnosed to have follicular carcinoma of thyroid in 2004 and undergone left hemi thyroidectomy for the same, with metachronous primary Chondrosarcoma involving the left hip bone in 2015 & Ewing’s sarcoma of right clavicle in 2017 with metastatic bilateral diffuse pulmonary infiltrates. The tumours were histologically distinct from the primary thyroid neoplasm, hence careful evaluation of the secondary primary malignancies is essential to treat them accordingly without dismissing them as metastases. Although surgery was advisable in this patient, he refused to undergo further surgical interventions and died of respiratory distress & carcinomatous cachexia in early 2018. Very scant data and studies are available on the development of multiple primary malignant neoplasms especially in the elderly population and the possibility of older cancer patients being at higher risk for developing second primaries.
Authors and Affiliations
Dr. Shwet Sabnis, Dr. Sayali Damle, Dr. T. K. Biswas
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