MUSHROOM POISONING INDUCED ACUTE LIVER FAILURE WITH DERANGED COAGULATION PROFILE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 66
Abstract
BACKGROUND Mushroom poisoning cases are frequently reported from Upper Assam during the monsoon season with varying but high mortality. Most of the cases reported from upper Assam are amatoxin poisoning. In one of our previous publications we have concluded that raised serum bilirubin, unconjugated bilirubin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were predictors of mortality. In this case series, we report 14 cases that came in the early spring of 2017 and we found that raised prothrombin time was a strong indicator of mortality in patients with mushroom poisonings. MATERIALS AND METHODS All patients who came to our Institute in 2017 with alleged history of mushroom poisoning were included in our study. A detailed history was taken and proper clinical examinations were done. Biochemical tests were done and correlated with patient’s outcome. All patients were treated according to our Institutional protocol. RESULTS Fourteen (14) adults were included in the series with eight (8) males and six (6) females. Four (4) patients expired and ten (10) survived. The patients who died had significant high liver enzymes. They also had significantly higher prothrombin time (mostly above 50 seconds), whereas in those patients who survived their average prothrombin time was 15.9 seconds initially (on day two of ingestion of mushroom) and 11.7 seconds during recovery (day eight of ingestion of mushroom). CONCLUSION We conclude that high Prothrombin time, especially more than 50 seconds, is associated with high mortality in patients with mushroom poisoning
Authors and Affiliations
Anupama Dutta, Pranjal Kumar Dutta, Swarup Kar
Keywords
Related Articles
- EP ID EP231913
- DOI 10.14260/Jemds/2017/1036
- Views 87
- Downloads 0
CLINICAL AND EPIDEMIOLOGICAL PROFILE OF BREATH HOLDING SPELLS (BHS)- AN ANALYSIS OF 115 CASES
BACKGROUND Breath holding spells are common in non-epileptic, repetitive, paroxysmal events in young infants and children often considered as seizure mimics/ confused with seizure disorder can be a frightening experience...
INFLUENCE OF MATERNAL FACTORS ON FOETAL MALNUTRITION USING CAN SCORE ASSESSMENT- A TERTIARY CARE CENTRE EXPERIENCE
BACKGROUND Potential conditions that predispose babies to being small at birth are quite common in tropical practice. Several factors may predispose to SGA delivery.1 Maternal factors known to contribute to foetal malnut...
COMPARISON OF BILIARY LEAKAGE IN LAPAROSCOPIC AND OPEN CHOLECYSTECTOMY
BACKGROUND Laparoscopic surgery is unsafe and technically impossible in case a gall-bladder disease has changed the usual anatomic landmarks. Though, open cholecystectomy has fewer incidents of biliary leakage, the risk...
COMPARATIVE STUDY OF BUPIVACAINE WITH FENTANYL VS BUPIVACAINE WITH FENTANYL PLUS MORPHINE IN SPINAL ANAESTHESIA FOR LOWER SEGMENT CAESAREAN SECTIONS
BACKGROUND Anaesthesiologists all over the world are facing challenges to manage increasing number of caesarean deliveries. Central neuraxial techniques of subarachnoid blockade with 0.5% Bupivacaine heavy solutions in d...
EARLY LAPAROSCOPIC APPENDICECTOMY IN MANAGEMENT OF APPENDICEAL MASS
BACKGROUND Acute appendicitis is a most common surgical emergency. Approximately, 10% of acute appendicitis patients present with appendiceal mass. Surgical management of appendiceal mass remains controversial. Majority...