Myasthenia with interesting systemic associations – A case series
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 3
Abstract
Myasthenia gravis MG is an autoimmune disorder with a highly variable clinical expression Ocular symptoms are the presenting features in 40 patients but MG is restricted to ocular muscles in 15 Myasthenia gravis is often associated with other autoimmune diseases Case details of ten myasthenic patients visiting ophthalmology department over two years in a tertiary care hospital were analyzed Five of them had interesting systemic associations One patient presented with coexisting thyroid ophthalmopathy and ocular myasthenia Because of the clinical overlap of ocular manifestations in myasthenia and Graves disease one of the two conditions may be missed Two patients had thymic mass Presence of thymoma and prognostic implications are highlighted One patient had thymic cyst pemphigus and diabetes mellitus This assortment of autoimmune conditions has not been reported in literature One patient had associated Parkinsons disease Myasthenia gravis presents with a highly variable clinical spectrum and is associated with a cluster of autoimmune diseases This unfortunate association is not widely appreciated This report highlights the importance of detecting systemic associations of MG The clinical relevance of these associations in diagnosis and management of myasthenia are discussed Keywords Myasthenia gravis Pemphigus Thyroid ophthalmopathy Thymoma
Authors and Affiliations
Muthu Krishnan Vallinayagam, Datta Gulnar Pandian, Vasudev Anand Rao
Keywords
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- EP ID EP474278
- DOI 10.18231/2395-1451.2018.0094
- Views 82
- Downloads 0
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