Mycobacterium Tuberculosis
Journal Title: International Journal of Biomedical and Advance Research - Year 2016, Vol 7, Issue 5
Abstract
Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. It is caused by a bacterial microorganism, the tubercle bacillus or Mycobacterium tuberculosis. Although TB can be treated, cured, and can be prevented if persons at risk take certain drugs, scientists have never come close to wiping it out. Diagnosis still depends largely on sputum microscopy, which is unsuitable for a large number of patients. The efficacy of the BCG vaccine is limited. Major obstacle in the cure and prevention of tuberculosis is posed by the latent or persistent M. tuberculosis infection. This is due to the fact that most of the currently available drugs are ineffective against latent infection. Scientist are searching for new targets for mycobacterium tuberculosis disease through biological studies (Proteonomics, Bioinformatics) then Synthetic modification in existing drug & study of some naturally existing drug. This review is useful to study the disease tuberculosis, Bacillus Characteristics, Clinical aspect, drug resistance study, treatment and study of new drug target for mycobacterium tuberculosis.
Authors and Affiliations
S. C. Kale, M. K. Kale, Sarita Singhal
Keywords
Related Articles
- EP ID EP364309
- DOI 10.7439/ijbar.v7i5.3193
- Views 79
- Downloads 0
A profile of acute self drug poisoning: Our experience in a tertiary care medical college teaching hospital
Background:Drug overdose can be accidental or deliberate posing a significant source of morbidity, mortality and health care burden. Drug over doses may be seen at any age and is particularly common among teenagers. It i...
Maternal and perinatal outcome in pregnancy with severe anaemia
Anemia is the most preventable cause of maternal and perinatal mortality and morbidity. This study was carried out to evaluate the maternal and perinatal outcome in pregnancy with severe anaemia. This hospitalized based...
Study of Maternal and Perinatal outcome in moderate to severe degree iron deficiency anaemia in rural community
Background: Anaemia is the commonest medical disorder associated with pregnancy. It contributes to one fifth of the maternal deaths and large number of preterm deliveries and low birth weight babies in India. Objectives...
Formulation and in vitro evaluation of Metformin HCl mucoadhesive tablets for NIDDM
The objective of the present work was to develop an oral Mucoadhesive Metformin hydrochloride tablet for the sustained-release. Metformin hydrochloride (HCl), a biguanide, has a relatively short plasma half-life and low...
Analysis of risk factors for deep vein thrombosis of the lower extremities
Deep vein thrombosis (DVT) is a common disease that occurs in most medical disciplines. It remains a frequent disease in which the major complication is pulmonary embolism (PE). Both DVT and PE occurring most frequently...