Myocardial Protection in Aortic Valve Replacement with Severe Aortic Stenosis: A Comperative Study between Del Nido and HTK Solution
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10
Abstract
Both Delnido and HTK Cardioplegia provides excellent myocardial protection and reduces the frequency of cardioplegia administration which allows uninterrupted operation and also reduces ‘x’-clamp timing. Both helps smooth myocardial recovery with post operative minimal inotropic support. But in aortic valve replacement in severe aortic stenosis with hypertrophied myocardium delnido cardioplegia provides poor protection where HTK provides better. Material and Methods: Twenty adult patients devided into two groups, Group-A (n=10) received delnido cardioplegia and Group-B (n=10) received HTK cardioplegia, underwent aortic valve replacement in severe aortic stenosis with hypertrophid myocardium. In both group same dose of cardioplegia (20ml/kg) was administered through anterograde route. Results: In group –B after valve replacement cardiac function was satisfactory with good ejection fraction, no rhythm disturbances occurred, and hemodynamics was well maintained with minimum inotropic support where in group-A in 40%cases VT/VF, in 20% case low cardiac output, 60% cases needed high inotrope with prolonged ventilatory support. Conclusion: HTK cardioplegia provides better myocardial protection in aortic valve replacement in severe aortic stenosis with hypertrophied myocardium
Authors and Affiliations
Kamal Das
Keywords
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