Myxofibrosarcoma of the Breast in a Young Pregnant Woman: A Case Report and Review of the Literature
Journal Title: Middle East Journal of Cancer - Year 2017, Vol 8, Issue 1
Abstract
Sarcomas of the breast are rare and comprise less than 1% of mammary cancers. Myxofibrosarcoma as an unusual variant of malignant fibrous histiocytoma in the breast and during pregnancy has not previous been reported in the literature. We present the case of a 32-year-old woman with a rapidly growing subcutaneous left breast mass that appeared during her first pregnancy. After ultrasonography and core needle biopsy, she underwent a modified radical mastectomy. Pathologic examination revealed a multinodular subcutaneous mass with characteristic microscopic features consistent with myxofibrosarcoma. Immunohistochemistry findings supported the diagnosis and excluded other differential diagnoses. There has been no consensus about proper management and surveillance in these rare groups of malignancies, however wide local excision and adjuvant treatment for moderate and high grade tumors are recommended.
Authors and Affiliations
Fatemeh Nili, Elham Asadinejad, Hana Saffar, Alireza Ghanadan
Keywords
Related Articles
- EP ID EP298133
- DOI -
- Views 107
- Downloads 0
Investigating the Levels of Shed Extracellular Domain of HER2 Protein in the Sera of Bladder Cancer Patients
Background: Receptor tyrosine-protein kinase ERBB2, also known as human epidermal growth factor receptor-2 (HER2), is heterogeneously expressed in a variety of human cancers, including bladder cancer. Based on previous s...
Salivary Parameters as Predictive Markers for Radiation-induced Treatment Response in Head and Neck Cancers: An Investigational Study
Background: This study evaluates the predictive significance of salivary amylase, glutathione, lipid peroxides, and lactate dehydrogenase in the treatment of head and neck cancer patients who undergo curative radiotherap...
Analysis of EVI1 Gene Expression in Acute Myeloid Leukemia Patients in the Northeast of Iran
Background: Acute myeloid leukemia (AML) is a heterogeneous disease characterized by increasing immature blood cells in the bone marrow. Aberrant expression of specific genes is a common finding in AML. The proto-oncogen...
Prognostic Value of KI6 Biomarker to Predict Short Term Prognosis of Low Grade Cervical Intraepithelial Neoplasia in Human Papilloma Virus Negative and Positive Patients
Background: Cervical cancer is the most common gynecologic cancer in developing countries. Although this malignancy is preventable, problems exist with screening this cancer. Numerous studies have researched immunohistoc...
Clustering of Breast Cancer Cases among Women from Kurdistan Province, Iran: A Population-based Cross-sectional Study
Background: Spatial analysis is one of the required tools of epidemiology and public health sciences. This study intends to detect significant clusters of breast cancer cases in Kurdistan Province, Iran. Methods: We obt...