N-chlorotaurine and N-bromotaurine Combination Regimen for the Cure of Valacyclovir-unresponsive Herpes Zoster Comorbidity in a Multiple Sclerosis Patient
Journal Title: International Journal of Medical and Pharmaceutical Case Reports - Year 2016, Vol 7, Issue 2
Abstract
Aims: Skin herpes zoster frequently affects immunocompromised patients including multiple sclerosis patients that belong to a distinct category of autoimmunity. Although considered a manageable condition, non-immunocompetent patients are suboptimally targeted by the gold standard valacyclovir treatment. In the case presented here, a new endogenous antiseptic treatment was applied. Presentation of Case: We describe a recurrent multiple sclerosis patient with herpes zoster skin infection, who was unresponsive to cotreatment with valacyclovir. Topical application of 0.8% N-chlorotaurine twice daily for four days resulted in immediate symptom resolution including loss of pain. Alternating application of 0.8% N-chlorotaurine and 1.0% N-bromotaurine in the next three days led to rapid healing. Discussion and Conclusion: This is the first case where natural taurine haloamines (N-chlorotaurine and N-bromotaurine), which are involved in innate immunity, were applied in reactivated, painful herpes zoster. The rapid clinical healing observed suggests specific investigations of the therapeutic effect of these compounds in this indication.
Authors and Affiliations
Anthony M. Kyriakopoulos, Stella Logotheti, Janusz Marcinkiewicz, Markus Nagl
Keywords
Related Articles
- EP ID EP327745
- DOI 10.9734/IJMPCR/2016/25476
- Views 83
- Downloads 0
A Case of Secondary Syphilis Presenting with a Vaginal Mass: A Case Report
Syphilis is an infectious venereal disease caused by the Treponema pallidum that presents with variable clinical manifestations. Herein we present an atypical case of secondary syphilis presenting with vaginal mass as th...
Hemoptysis in a Young Adult with Congenital Cystic Adenomatoid Malformation of the Lung: Case Report
Congenital cystic adenomatoid malformations (CCAM), also named congenital pulmonary airway malformation s (CPAM) are multicystic masses of segmental lung tissue with abnormal bronchial proliferation. There is failure of...
Isoniazid-Induced Psychosis in 2 Children Treated for Tuberculosis: Case Reports and Literature Review
Aims: To report isoniazid-induced psychosis in 2 children treated for Tuberculosis (TB) as a reminder or an alert to clinicians and other health workers. Presentation of Cases: Isonicotinic acid hydrazide (INH) is common...
Lung Adenocarcinoma with Coexistent Primary Hyperparathyroidism
The simultaneous presence of lung carcinoma and primary hyperparathyroidism, both causative conditions for hypercalcemia, is quite rare. A 56-year-old woman was diagnosed with hypercalcemia, caused by asymptomatic primar...
Esthetic Rehabilitation with Zirconia Based Crowns
This article describes a case of discolored central incisors treated by using Zirconia based crowns. A 25 year old female patient presented to the department of Fixed Prosthodontics. She requested the improvement of her...