NANOMATERIALS BASED ACETYLCHOLINESTERASE BIOSENSORS FOR ORGANOPHOSPHORUS COMPOUNDS DETECTION: REVIEW
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 2
Abstract
Due to intense pressure on agriculture for supporting exponentially growing population pesticides are used on an alarming scale. As these pesticides contain Organophosphorus (OP) compounds which are highly toxic and interfere with functioning of enzyme Acetylcholinestrase (AChE) and finally affecting Central Nervous System (CNS). So, there is an urgent need to monitor OP compounds concentration regularly in the marketed food products and even in the environment (water, soil). Here we focus on the different nanomaterials used for the fabrication of the AChE biosensors for detection of OP compounds which is based on inhibition of AChE. The merits and demerits of the different nanomaterials which are being used as supports are also discussed. The mode of detection, detection limit, linearity range, time of incubation, storage stability of the biosensors is also reviewed. Nanomaterial as an important class of supports used for the AChE biosensors due to their valuable properties. Among all the nanomaterials used Gold nanoparticles (AuNPs) have gained an advantage as they are explored with time.Â
Authors and Affiliations
Vikas Dhull, Neeraj Dilbaghi
Keywords
Related Articles
- EP ID EP579024
- DOI -
- Views 71
- Downloads 0
A VALIDATED ISOCRATIC RP-HPLC METHOD FOR CONCURRENT ESTIMATION OF GYMNEMAGENIN, GALLIC ACID AND 18Î’-GLYCYRRHETINIC ACID IN POLYHERBAL FORMULATION
Objective: To develop and validate a simple, precise, selective, and accurate reversed phase high performance liquid chromatography method for concurrent analysis of gymnemagenin, gallic acid and 18β-glycyrrhetinic acid...
SYNTHESIS OF NOVEL CYCLOHEXANONE DERIVATIVES AS BCR-ABL T1351 INHIBITORS
Objective: Several 3(rd) generation inhibitors are being developed for the treatment of patients with Chronic myelogenous leukemia (CML). The present work mainly aims to discover novel small molecular inhibitors against...
STUDY OF IMMOBILIZATION OF UREASE ON PVA-NANO NiFe2O4 NANOCOMPOSITE FOR BIOSENSOR APPLICATIONS
Objective: The main objective of this study to prepare the highly sensitive and high-performance biosensor using Nickel ferrite (NiFe2O4) nanoparticles and biological agent (enzyme) for the respective biosensor.Methods:...
PHYLOGENETIC STUDY OF THREE LINES CAVIA PORCELLUS (GUINEA PIGS) PERU, ANDINA AND INTI, "EL PRADO" FARM, UNIVERSITY OF THE ARMED FORCES – ESPE IN ECUADOR
Objective: The present study was undertaken to investigate the morphological and to establish molecular relations between three lines of guinea pigs, which are phenotypically selected and form the basis for a molecular m...
IN VITRO STUDY ON RELEASE OF BIOACTIVE ANTIMICROBIAL COMPOUNDS FROM DAIRY PRODUCTS BY CERTAIN PROMISING PROBIOTIC LACTOBACILLUS STRAINS
Objective: The antimicrobial activity and Probiotic properties of Lactobacillus species were evaluated. The antimicrobial compound of potent antimicrobial probiotic Lactobacillus was purified by column chromatography and...