Nanotechnology in Cancer: an Overview on Importance of Patient’s Screening in Nanomedicine Based Combinational Therapies
Journal Title: Archives of Nanomedicine: Open Access Journal - Year 2018, Vol 1, Issue 3
Abstract
Targeting cancer using nanomedicine is not a new concept. Earlier focus was on targeted therapy and then concept came of combinational therapy. Along with the use of combinational therapies, Pre-selection screening of the patients using molecular approach is equally important to achieve the maximum benefit to the cancer patients. Nanotechnology is the division of technology which deals with the design, production, characterization, and applications of the matter at nano scale in terms of size and shape ranging between 1 to 100nm [1]. Nanomaterials can be engineered either solid or hollow structure with different sizes, shapes along with different chemical compositions with the properties to deliver higher ratio of surface area over volume [2-4]. The applications of the nanotechnology are very diverse in the field of science ranging from Physics, chemistry to biological Science [5]. Nanotechnology is very useful in medical applications for the prevention, diagnosis as well as cure of diseases at molecular level, due to similarity in scale of biological molecules and nanomaterials, Applications of nanomaterials being designed for the biological systems include ability to cross the biological barriers for the transport of therapeutic or diagnostic materials so that efficient access to biological molecules, maximum molecular interaction and detection of molecular changes can take place in a high throughput manner [6-8]. To target cancer, several nanotechnology based drug delivery vehicles, nanomedicine, diagnostic devices, and contrast agents got approved from Food and Drug Administration (FDA) or are under clinical investigations [3,9,10]. Current overview describes the past, present and future prospects of nanomaterials in biological systems to target cancer.
Authors and Affiliations
Subodh Kumar, Rahul Soloman Singh, Phulen Sarma, Dibbanti Harikrishna Reddy, Sukhjinder Singh, Ashutosh Singh, Bikash Medhi
Keywords
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- EP ID EP583421
- DOI 10.32474/ANOAJ.2018.01.000112
- Views 74
- Downloads 0
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