Naproxen Delayed Release Drug Delivery Systems

Journal Title: Journal of Pharmaceutical and Medicinal Chemistry - Year 2017, Vol 3, Issue 1

Abstract

Delayed release drug delivery systems are a major advance towards solving problems concerning the stability and solubility of drug in gastrointestinal tract and thereby release the drug in the small intestine. Naproxen is a non-selective Cyclooxygenase (COX) inhibitor, which is insoluble in acidic environment and cause gastric distress or irritation. In order to prevent the gastric irritation, Naproxen is designed to formulate as Enteric coated tablet which is more soluble in pH 6.8 at small intestine.

Authors and Affiliations

Gandla Kumaraswamy

Keywords

Related Articles

RP – HPLC Method Development and Validation for Simultaneous Estimation of Irbesartan, Amlodipine and Hydrochlorothiazide in Bulk and Tablet Dosage Forms

A reverse phase high performance liquid chromatographic method has been developed for the simultaneous estimation of Irbesartan, Amlodipine besylate and hydrochlorothiazide in bulk and Pharmaceutical formulation using RP...

Evolution in Medicinal Chemistry of Prazolopyrimidine Derivatives as Anticancer Agents

Pyrazolopyrimidines are the fused heterocyclic ring systems which structurally resemble with purines, and exhibit important biological actions. Pyrazolopyrimidines derivatives have great importance in the field of chemic...

A Novel Stability Indicating RP-HPLC Method for Determination of Sofosbuvir in Bulk and Tablet Dosage

The proposed work was accurate and precise stability indicating RP-HPLC method has been developed and validation of Sofosbuvir, in tablet dosage form. The separation was achieved on a Kromasil C18 (4.6×250 mm, 5µ) column...

Effect of Microwaving and Some Cooking Methods on Enrofloxacin in Chicken Meat

The present study was undertaken to determine the effects of microwaving and some cooking methods like boiling and deep-frying on Enrofloxacin (ENR) in chicken meat. Chicken meat samples incurred with known concentration...

Recent Trends in Animal Origin Food Drug Residue: A Public Health Concern

The demand for animal products in the market is increasing day by day to fulfill the needs of ever growing human population. Failure to meet up public demand and the desire of making a quick profit makes the farmer adopt...

Download PDF file
  • EP ID EP469405
  • DOI 10.21088/jpmc.2395.6615.3117.5
  • Views 118
  • Downloads 0

How To Cite

Gandla Kumaraswamy (2017). Naproxen Delayed Release Drug Delivery Systems. Journal of Pharmaceutical and Medicinal Chemistry, 3(1), 39-48. https://europub.co.uk/articles/-A-469405