SCREENING OF THE ANTIINFLAMMATORY ACTIVITY OF “TRIANTHEMA PORTULACASTRUM” IN ACUTE MODELS OF INFLAMMATION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 30
Abstract
[b] BACKGROUND[/b]: There are many anti-inflammatory drugs available but all of them do have a significant adverse effect profile. Trianthema portulacastrum is known in Ayurveda since centuries for its medicinal values. So the current study was undertaken to evaluate the antiinflammatory effects of this plant in acute inflammation. [b]MATERIALS AND METHODS[/b]: Albino rats were treated with whole plant ethonolic extract of Trianthema portulacastrum 100mgkg,indomethacin 20mgkg, orally with 2% gum acacia as suspending agent and the effects were observed in acute models of inflammation viz, carrrageenin induced paw edema and formalin induced peritonitis. [b]RESULTS[/b]: our study demonstrated that Trianthema portulacastrum exhibited significant anti-inflammatory activity in both the models. [b]CONCLUSION[/b]: Trianthema potrulacastum has got significant anti-inflammatory activity so further studies are needed in this direction.
Authors and Affiliations
Suresh Kendri, Umesh Wari
Keywords
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- EP ID EP143393
- DOI 10.14260/jemds/2015/757
- Views 49
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