STUDY OF RISK FACTORS CONTRIBUTING TO ADVERSE NEONATAL OUTCOME IN HYPERTENSIVE MOTHERS COMPARED TO NON HYPERTENSIVE MOTHERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 48
Abstract
[b]AIM[/b]: To study the various risk factors in hypertensive mothers that contribute to adverse neonatal outcome in the form of low birth weight when compared to non-hypertensive mothers. [b]SETTING:[/b] The study was conducted in the Inborn NICU and New born Follow up clinic of Department of Paediatrics in a rural Government medical college Hospital. STUDY DESIGN: Prospective cohort study. [b]MATERIALS AND METHODS: INCLUSION CRITERIA: CASES: [/b]Consecutive sample of mothers with pregnancy induced hypertension during the study period who have given consent for the study were interviewed and their live born babies were included as cases. [b]CONTROLS[/b]: Consecutive sample of live born babies born to non-hypertensive mothers in the same study period were included as controls. Exclusion Criteria: Babies with major congenital anomalies chromosomal anomalies, intrauterine death were excluded. [b]METHODOLOGY[/b]: Details of maternal risk factors were collected. Anthropometric parameters, systemic examination, development and maturity of the babies were assessed. [b]STATISTICAL TESTING[/b]: Significance testing was done using chi square test, odds ratio, analysis of risk ratios and correlation testing. P values greater than .05 were considered non-significant. Spss 16 Software package was used for statistical analysis. [b]RESULTS[/b]: The incidence of low birth weight in this study was 45.6% which is considerably higher than in controls (16.6%) and in the general population (19.1%). 33.8% of babies were preterm among the cases compared to 6.1% among controls.Among mothers with hypertension detected before 30 weeks, 90.3% had low birth weight babies. Among mothers with severe hypertension, 86.4% had low birth weight babies compared to 29.8% among those with mild hypertension.92.3% pregnancies with Doppler abnormalities had LBW. 70.8% of LBW babies had antenatal intra uterine growth restriction.90.1% of hypertensive mothers with albuminuria had associated LBW. 100% babies had low birth weight when mother had eclampsia and renal function abnormality. [b]CONCLUSION[/b]: Risk factors associated with hypertension have a link with low birth weight and adverse outcome in babies.
Authors and Affiliations
Swapna Pillai, Razin Nazarullah
Keywords
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- DOI 10.14260/jemds/2015/1206
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