A RANDOMIZED CLINICAL TRIAL COMPARING EFFICACY OF VITRECTOMY WITH INTRA VITREAL TRIAMCINOLONE ACETONIDE INJECTION AND SIMPLE VITRECTOMY IN PATIENTS WITH VITREOUS HAEMORRHAGE DUE TO PROLIFERATIVE DIABETIC RETINOPATHY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 21
Abstract
Proliferative diabetic retinopathy affects about 5-10%of the diabetic population. It is the advanced form of the disease due to ischemic changes and this indicates progression towards more devastating form ie; end stage diabetic eye disease leading to total blindness. The conventional treatment of this disease has been with laser photocoagulation of the ischemic areas. Serious vision threatening complications of diabetic retinopathy (Advanced Diabetic Eye Disease [ADED]) occur in patients who have not had laser therapy or in whom laser therapy has been unsuccessful. In these groups of patients the treatment is vitrectomy with varying results in regaining and maintaining the regained vision. So Intra Vitreal triamcinolone Acetonide [IVTA] injection has been tried in many centres, because of its anti inflammatory, anti angiogenic, cell migration inhibition properties. In this context to study the efficacy of intravitreal triamcinolone against simple vitrectomy was considered. The comparison of two modes of therapy is best done by a Randomized Controlled Trial. Such studies are not reported from elsewhere in India. Hence this study.
Authors and Affiliations
Rajeevan P, Mahadevan K
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