A RARE AND UNIQUE CASE OF ECCRINE SPIRADENOMA OF THE EYELID
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 11
Abstract
Rare group of tumors with potential for local destruction and metastasis, Taxonomically segregated into 2 main groups, as follows: those that are histologically similar to certain benign appendage tumors (e.g., sclerosing sweat duct carcinoma, porocarcinoma, malignant chondroid syringoma, malignant nodular hidradenoma, and malignant eccrine spiradenoma) and those that show a diverse array of histologic features, not recapitulating to any degree aspects of a benign counterpart derived de novo from any portion of the normal eccrine apparatus or result from the transformation of an existing benign eccrine tumor. An etiologic role for UVR has been suggested; Abbate et al reported that 5 out of 10 patients with MAC gave a prior history of radiation therapy. Chiller et al reported a potential etiologic role for UVR as they describe MAC predominantly affecting the left side of the face, corresponding to higher UVR exposures while driving. Immunosuppression has been known to increase the risk of nonmelanoma skin cancers, particularly squamous cell carcinomas, Harwood et al suggested that patients who are immunosuppressed have a propensity to also develop cutaneous appendageal tumors over their immunocompetent counterparts, with increased rates of both benign eccrine tumors and malignant eccrine tumors.
Authors and Affiliations
Padmini H. R, Dinesh P
Keywords
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- EP ID EP95553
- DOI 10.14260/jemds/447
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