A STUDY ON DYSLIPIDAEMIA IN CHRONIC KIDNEY DISEASE (CKD) WITH SPECIAL REFERENCE TO HAEMODIALYSIS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 28
Abstract
Dyslipidaemia is a common complication of CKD. It is also an independent predictor of cardiovascular disease, which is a major cause of mortality in these patients. AIMS AND OBJECTIVES ï· To study the levels of lipids in CKD. ï· Effect of haemodialysis on lipids. MATERIALS AND METHODS 250 patients of CKD were screened and out of them 118 patients with chronic renal failure associated with dyslipidaemia completed the study. Lipid variables were measured before and after 6 months of regular biweekly bicarbonate-based haemodialysis. Lipid variables were compared with 50 age and sex matched healthy controls. All the values were expressed in terms of mean and standard deviation and statistical analysis was carried out by using student âTâ test. RESULTS We found that the cholesterol level was maximally deranged followed by LDL and followed by triglycerides in the study group as compared to controls. There was reduction in total cholesterol, triglycerides, LDL, VLDL, while increment in mean HDL after dialysis. But the changes were statistically insignificant. CONCLUSION CKD is associated with dyslipidaemia even in younger age groups. The reduction in lipid profile was insignificant even after 6 months of haemodialysis and p value remained >0.05.
Authors and Affiliations
Shweta , Sandhya , Dhanveer , Prachi , Avriti
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