Acoustical behavior of some amino acids in aqueous disodium citrate solutions over temperature range (298.15-313.15) K
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 5
Abstract
Sound velocity, U, and density, ρ, of some amino acids viz. glycine, methionine, phenylalanine and tryptophan were determined in 0.1, 0.2 and 0.3 mol kg−1aqueous disodium citrate solutions as a function of concentration at 298-313.15K using DSA 5000M. The experimental data were further used to compute various acoustical parameters such as adiabatic compressibility, β, apparent molar compressibility, Φk, partial molar compressibility, Φ0k, transfer adiabatic compressibility, Φ0ktr, constant, Sk, and the hydration number, nH. The transfer adiabatic compressibility shows the supremacy of hydrophilic-ionic interactions under hydrophobic–ionic interactions. The above-mentioned parameters are relevant for the efficiency of mediation in pharmacology and can be interpreted in terms of structure-making or structure-breaking ability of these amino acids in the solution.
Authors and Affiliations
Muhammad Asghar Jamal , Muhammad Kaleem Khosa , Majid Muneer , Fazal-ur-Rehman , Muhammad Jawad Saif , Haq Nawaz Bhatti , Sadaf Naz , Jaweria Javed
Keywords
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