Antimicrobial and antioxidant activities and chemical characterization of essential oils of Thymus vulgaris, Rosmarinus officinalis, and Origanum majorana from northeastern México
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 1
Abstract
There have been no reports of antifungal activity and composition of extracts from Thymus vulgaris, Rosmarinus officinalis or Origanum majorana from northeastern México. Antifungal activity of these oils against Trichophyton rubrum, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporum gypseum, Microsporum canis and Epidermophyton floccosum was measured by diffusion assay. Additionally, antibacterial and antioxidant activities were evaluated. Antibacterial activity against Staphylococcus aureus and Streptococcus pyogenes was examined by microdilution. Antioxidant activity was assessed by 2,2-difenil-1-picrilhidracil reduction test. The plant oils were characterized by both GC/MS and GC/FID. Oils of T. vulgaris and O. majorana showed growth inhibition activity against dermatophytes, especially T. vulgaris oil, which completely inhibited growth of all tested dermatophytes. The oils also showed bioactivity against bacteria, with minimum inhibitory concentration (MIC) values between 62.5 and 500 g/mL. The antioxidant activity of the oils was low, with effective concentration (EC50) values >250g/mL. The major components in the oils were as follows: T. vulgaris, o-cymene, -terpinene, thymol and carvacrol; R. officinalis, terpinen-4-ol and 1,8-cineole; O. majorana, terpinen-4-ol and thymol.
Authors and Affiliations
Laura Guerra-Boone , Rocío Alvarez-Román , Ricardo Salazar-Aranda , Anabel Torres-Cirio , Verónica Mayela Rivas-Galindo , Noemí Waksman de Torres , Gloria González , Luis Alejandro Pérez-López
Keywords
Related Articles
- EP ID EP153022
- DOI -
- Views 99
- Downloads 0
Counter effects of N. Sativa L. and P. ovataL. on indicative markers ofnon alcoholic fatty liver disease
The broad spectrum of non-alcoholic fatty liver disease (NAFLD) diseases ranges from simple liver inflammation to steatosis, leading to fibrosis and cirrhosis. Four groups of weaning (30g) Rattusnorvegicus were des...
[u][/u] Preliminary evaluation of antimicrobial activity of cream formulated with essential oil of Trachyuspermum ammi
: In our present research we studied physiochemical properties and antimicrobial activity of T. ammi (Trachyuspermum ammi) seeds. The seeds yielded 2.86% essential oil. Refractive index, specific gravity, acid valu...
Current trends in treatment of obesity in Karachi and possibilities of cost minimization
Our study finds out drug usage trends in over weight and obese patients without any compelling indications in Karachi, looks for deviations of current practices from evidence based antihypertensive therapeutic guid...
Effect of Lactobacillus species on Streptococcus mutans Biofilm formation
Streptococcus mutans is the primary pathogen responsible for initiating dental caries and decay. The presence of sucrose, stimulates S. mutans to produce insoluble glucans to form oral biofilm also known as dental...
Distribution and drug resistance profile of methicillin-resistant Staphylococcus aureus after orthopaedic surgery
This paper is aimed to comprehend clinical distribution and drug-resistance situation of methicillin-resistant Staphylococcus aureus. This study applied automatic microbe instrument Microscan W /A 96 for strain ide...