Antiretroviral Drug Substitution Practice in the Treatment Of HIV/TB Co- Infection
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 5
Abstract
This was a study to evaluate antiretroviral drug substitution practice in the treatment of HIV/TB co-infection. METHODS: The study was a retrospective review of HIV patients who were treated for tuberculosis over a 2 year period at the HIV clinic of the Federal Medical Centre, Makurdi. All patients who registered for HIV services at that period were reviewed. The case notes of those patients who were treated for tuberculosis during the study period were retrieved, data extracted for analysis using SPSS version 16. Case notes with insufficient information were excluded. RESULTS: 450 patients were screened for TB, 75 had active TB giving a TB prevalence of 16.7%. One third (33.3%) were aged 30-39 years, 22 (29.3%) were 40-49 years, 17 (22.7%) were <30years and 11 (14.7%) were ≥50years old. Majority 46 (61.3%) of the patients were females. Over half 41(54.7%) had secondary or tertiary education and were single, divorced, separated or widowed. Only 28 (37.3%) were on Efavirenz, an equal number 27 (36%) were on a Nevirapine while 2 (2.7%) were on a Protease Inhibitor. CONCLUSION: This study showed poor compliance with Nigerian treatment protocol for TB/HIV coinfection. Effort to improve TB control in HIV patients are urgently needed
Authors and Affiliations
Godwin . I. Achinge
Keywords
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