ASYMPTOMATIC BACTERIURIA IN HIV/AIDS PATIENTS: OCCURRENCE AND RISK ASSOCIATED WITH LOW CD4 COUNTS.
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 19
Abstract
[b] BACKGROUND[/b]: People living with HIV/AIDS with progressive immune dysfunction have an augmented risk of Urinary tract infection, both symptomatic and asymptomatic, in comparison to non-infected individuals. [b]AIMS[/b]: This prospective study was planned to know the frequency of asymptomatic bacteruria (ASB) in HIV sero-positives and its correlation to their immune status. Conventional culture method was compared with screening test using SD Urocolor TM 10 test strips for the presence of infection. Antibiogram of isolated uropathogens were analysed to understand the trends of drug resistance. [b]SETTINGS AND DESIGN[/b]: Prospective Cohort Study. [b]MATERIALS AND METHODS[/b]: Clean catch midstream urine samples collected from 270 HIV seropositive patients and 100 seronegative controls were screened for ASB by Urostrip urinalysis, Gram stain and culture. Antibiogram of significant growth isolates was done by Kirby-Bauer disc diffusion method. Their immune status was evaluated by CD4 + cell counting. [b]STATISTICAL[/b] [b]ANALYSIS USED[/b]: Sensitivity, Specificity, Odds ratio, Fisher extract test. [b]RESULTS[/b]: ASB was detected in 5.6% (15/270) of HIV sero-positives and 1% (1/100) of seronegatives controls.13/15 HIV seropositive ASB cases had CD4 cell counts < 350 cells/ μL. The gram stain and urostrips had sensitivity of 93.33% & 80% and a specificity of 95.68% & 60.39% respectively. [b]CONCLUSIONS[/b]: Occurrence of ASB was significantly high among the HIV sero-positives with CD4 cell counts < 350 cells/ μL. Conventional culture and gram staining continue to be the proficient methods for detecting ASB. Cotrimaxazole prophylaxis hardly influenced the presence of ASB in HIV sero-positives
Authors and Affiliations
Rashmi K. S, Ravikumar K. L, Jagadeesh , Nimitha , Bhagyashree H. N
Keywords
Related Articles
- EP ID EP143368
- DOI 10.14260/jemds/705
- Views 84
- Downloads 0
ROLE OF ULTRASOUND IN EVALUATION OF NON-TRAUMATIC SHOULDER PAIN
BACKGROUND Shoulder is one of the anatomical areas which is most commonly evaluated with musculoskeletal ultrasonography. The objectives of this study were1. To evaluate the role of ultrasound in non-traumatic shoulder p...
EARLY SURGICAL INTERVENTION IN DIABETES RELATED INFECTIONS: THE ANSWER TO EARLY HEALING AND SHORTENED HOSPITAL STAY?
BACKGROUND Diabetes mellitus is a growing problem with India, fast becoming the diabetic capital. A significant number of diabetics in our country, particularly in rural areas, do not have good glycaemic control, either...
OUTCOME OF INSTRUMENTAL VAGINAL DELIVERIES IN REFERRED CASES
[b]INTRODUCTION[/b]: Instrumental vaginal deliveries are important procedures. Performed in indicated cases and attending to the well laid criterias will reduce the fetal and maternal morbidity. These assisted...
ROLE OF FUNDUS FLUORESCEIN ANGIOGRAPHY IN EVALUATION OF RETINAL DISORDERS
BACKGROUND Retinal disorders are the leading cause of legal blindness in the age group of 20 to 65 years. Approximately 18 million people in India have severely impaired vision due to retinal diseases. It has been nearly...
ANALYSIS OF INDICATIONS AND COMPLICATIONS OF ELECTIVE CAESAREAN SECTION IN PRIMI AT A TERTIARY CARE CENTRE, VIJAYAWADA, ANDHRA PRADESH, INDIA
BACKGROUND Most common operation performed in any obstetric institute is caesarean section. Worldwide, there is increasing rate of caesarean section. Most important indication is repeat caesarean section. Hence, unless w...