BACTERIOLOGICAL PROFILE OF OSTEOMYELITIS CASES WITH SPECIAL REFERENCE TO ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ISOLATES IN A TERTIARY CARE HOSPITAL OF EASTERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 53
Abstract
BACKGROUND Despite advances in medical and surgical therapies, the management of osteomyelitis is an increasing challenge to clinicians due to growing resistances to antibiotics. The present study was conducted to determine the bacteriological profile of cases of osteomyelitis and also to ascertain the antibiotic susceptibility pattern of these isolates to prevent unnecessary morbidity and mortality. OBJECTIVE The proposed study was carried out to isolate, identify, and characterize the bacterial strains isolated from cases of acute and chronic osteomyelitis and to ascertain the antimicrobial susceptibility pattern of these isolates. MATERIAL AND METHODS A total of 97 samples like pus or exudates or pieces of necrotic tissues were collected during surgery if possible, otherwise aspirated. All samples were subjected to Gram staining and culture. Various organisms were identified by standard methods. The Kirby-Bauer method was employed to perform the antimicrobial susceptibility on Mueller-Hinton agar [MHA]. For detection of methicillin-resistant Staphylococcus aureus [MRSA], MHA supplemented with 4% NaCl was used. RESULTS A total of 94 organisms were isolated from indoor patient department. Of the unimicrobial isolates, Escherichia coli (19.0%) were the main organism. Amongst the polymicrobial growth, the common combination was between Staphylococcus aureus and E. coli. The most common factor leading to osteomyelitis was trauma/accidents, 49.5% (48/97). S. aureus, was the common organism isolated from trauma/accident (83.3%) cases. Of the total, 30.2% (16/53) of strains were MRSA. 50% of MRSA isolates were found in patients with orthopaedic implants. Among the gram-negative bacilli, E. coli showed maximum resistance to amoxicillin (100%) followed by P. aeruginosa that showed maximum resistance to ciprofloxacin (77.7%). CONCLUSION Our study will thereby guide the clinicians in choosing appropriate antibiotics, which not only contribute to better treatment, but the judicious use of such antibiotics will also help in preventing emergence of resistance to the drug, which are still sensitive.
Authors and Affiliations
Anupama , Priyanka Biswas, Aninda
Keywords
Related Articles
- EP ID EP164774
- DOI 10.14260/jemds/2016/807
- Views 74
- Downloads 0
STRONGYLOIDES STERCORALIS INFESTATION IN AN IMMUNOCOMPETENT HOST- A CASE REPORT
PRESENTATION OF CASE A 59-year-old agriculturist with recent venture into poultry farming presented with history of post-prandial vomiting, gastric upset, loss of appetite and weight loss of 20 days duration. Investigati...
A CLINICAL STUDY ON ACUTE PANCREATITIS AND ITS DIFFERENT ETIOLOGIES IN BOWRING & LADY CURZON HOSPITALS, BENGALURU
There are various etiological factors causing acute pancreatitis; of them to identify the most common etiological factor affecting the severity of symptoms, complications and mortality in acute pancreatitis. Acut...
LAPAROSCOPIC ASSISTED SURGERY IN COLORECTAL CANCER: OUR EXPERIENCE
BACKGROUND Laparoscopically assisted surgery was first conducted in 1990 for a patient undergoing colectomy for cancer. A recent increase in the number of reports, retrospective analyses, and trials has now provided suff...
A STUDY OF PULMONARY MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS
BACKGROUND Systemic Lupus Erythematosus (SLE) is a multisystem disease that is caused by tissue damage resulting from antibody and complement–fixing immune complex deposition. There is a wide spectrum of clinical present...
OVARIAN AND ADNEXAL TORSION: SPECTRUM OF IMAGING FINDINGS WITH INTRA-OPERATIVE AND PATHOLOGIC CORRELATION
[b] OBJECTIVE[/b]: The purpose of this study was to review the role of ultrasound in prompt pre-operative diagnosis of adnexal torsion so that no time is wasted before surgery and salvage of ovarian tissue be a...