Carotenoids From Red Fruit (Pandanus Conoideus Lam.) Extract Are Bioavailable : A Study In Rats
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 2
Abstract
: Red Fruit (Pandanus conoideus Lam.) is a Papuan indigenous fruit. This fruit has the potential of becoming functional food because of its carotenoid compounds that acts as an antioxidant and provitamin A. The high content of carotenoid in red fruit promotes the fruit empirically to prevent and cure various diseases. However, it has not been known how much carotenoid from red fruit can be absorbed and utilized by the body. This study aims (1) to evaluate the carotenoid bioavailability of red fruit extract; and (2) to the determine retinol accumulation factor in rat liver. The study was conducted with the approaches of carotenoid depletion and repletion. After 14 weeks depletion period and 2 weeks repletion period, it was obtained that retinol accumulation factor in red fruit extract group was 49.02 and positive control group was 42.41. This indicate that to generate 1 μg retinol in rat liver required 49.02 β-carotene from red fruit extract or 42.41 μg of pure β-carotene.
Authors and Affiliations
Mathelda Kurniaty Roreng , Nurheni Sri Palupi , Endang Prangdimurti
Keywords
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- EP ID EP99404
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