Comparative study on lipid profile in tobacco chewers and nontobacco chewers
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 2
Abstract
Background: Tobacco chewing is associated with millions of cases of chronic obstructive pulmonary diseases (COPD) and coronary artery diseases annually. Major forms of chewable tobacco contain toxicants and carcinogens. According to the World Health Report 2002, tobacco is the leading preventable cause of overall mortality as well as cardiovascular mortality worldwide. Aims and Objective: To reveal the effect of tobacco chewing on the lipid profile. Materials and Methods: This study was conducted to reveal the effect of tobacco chewing on the lipid profile in male subjects. The cross-sectional study was conducted in 60 male subjects aged 30–45 years. The subjects were divided into control group (n = 30) and study group (i.e., tobacco chewers; n = 30). All subjects were from either social class 2 or 3 according to Prasad’s modified social classification. About 5 mL venous blood sample was drawn after 10–12 h of fasting and lipid profile was analyzed. Results: No significant difference in anthropometric parameter of the control group and the study group was observed. Triglyceride and very-low-density lipoprotein cholesterol levels increased significantly (p < 0.001) in the study group (i.e., tobacco chewers) than in the control group. Total cholesterol and low-density lipoprotein cholesterol levels increased significantly (p < 0.05) in tobacco chewers than in the control group. The mean value of high-density lipoprotein cholesterol levels decreased but not significantly in tobacco chewers than in the control group. Conclusion: Strict measures should be taken up to control the prevalence of tobacco chewing habits and to prevent the risk for diseases such as cardiovascular diseases and COPD.
Authors and Affiliations
Qazi Rais Ahmed, Narendra Gupta, Sapna Goyal, Shahid Jamal Ansari
Keywords
Related Articles
- EP ID EP96167
- DOI 10.5455/njppp.2015.5.201120141
- Views 75
- Downloads 0
A randomized open-label study to compare the effects of amlodipine and cilnidipine on heart rate and proteinuria in subjects with hypertension with proteinuria
Background: Calcium channel blockers (CCBs) are a commonly used class of drugs for the treatment of hypertension. Cilnidipine is a novel CCB with a dual L/N-type CCB property, thus favoring additional renal and cardiovas...
Correlation of anthropometric indices with lipid profile in adult females
Background: The prevalence of dyslipidemia has increased manifold in the industrialized, developed, and the developing countries to the extent that it is becoming an escalating epidemic. Obesity, an important risk factor...
Teaching and learning educational tool preferences among 1st year dental students in physiology: A cross-sectional questionnaire survey
Background: Evaluation is an important process in teaching and learning strategies, which includes description, collection, and analysis of available tools for their effective outcome. Hence, it is important to understan...
Assessment of knowledge, attitude, and practices about prescribing fixed dose combinations among doctors - An observational study
Background: A fixed dose combination (FDC) comprises of two or more active drugs in a single dosage. The trend of prescribing FDCs is increasing in clinical practice. However, irrational prescribing of FDCs is a major he...
Effect of Balasana on cardiac parameters among healthy medical students
Background: Among many professional courses, MBBS found to be difficult to complete, where students are busy with studies throughout the course. They have less chances of relaxation. Sage Patanjali explained two limbs of...