Comparative study on lipid profile in tobacco chewers and nontobacco chewers
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 2
Abstract
Background: Tobacco chewing is associated with millions of cases of chronic obstructive pulmonary diseases (COPD) and coronary artery diseases annually. Major forms of chewable tobacco contain toxicants and carcinogens. According to the World Health Report 2002, tobacco is the leading preventable cause of overall mortality as well as cardiovascular mortality worldwide. Aims and Objective: To reveal the effect of tobacco chewing on the lipid profile. Materials and Methods: This study was conducted to reveal the effect of tobacco chewing on the lipid profile in male subjects. The cross-sectional study was conducted in 60 male subjects aged 30–45 years. The subjects were divided into control group (n = 30) and study group (i.e., tobacco chewers; n = 30). All subjects were from either social class 2 or 3 according to Prasad’s modified social classification. About 5 mL venous blood sample was drawn after 10–12 h of fasting and lipid profile was analyzed. Results: No significant difference in anthropometric parameter of the control group and the study group was observed. Triglyceride and very-low-density lipoprotein cholesterol levels increased significantly (p < 0.001) in the study group (i.e., tobacco chewers) than in the control group. Total cholesterol and low-density lipoprotein cholesterol levels increased significantly (p < 0.05) in tobacco chewers than in the control group. The mean value of high-density lipoprotein cholesterol levels decreased but not significantly in tobacco chewers than in the control group. Conclusion: Strict measures should be taken up to control the prevalence of tobacco chewing habits and to prevent the risk for diseases such as cardiovascular diseases and COPD.
Authors and Affiliations
Qazi Rais Ahmed, Narendra Gupta, Sapna Goyal, Shahid Jamal Ansari
Keywords
Related Articles
- EP ID EP96167
- DOI 10.5455/njppp.2015.5.201120141
- Views 63
- Downloads 0
A comparative study of handgrip strength among sedentary and non-sedentary workers
Background: India is a developing country with a rapid transformation in lifestyle including inappropriate diet and inadequate physical activity. More the physical activity greater will be the muscle strength. Handgrip s...
Green synthesis of Mangifera indica silver nanoparticles and its analysis using Fourier transform infrared and scanning electron microscopy
Background: Cost effective and environmentally favorable green synthesis of metallic nanoparticles is a fast growing research in nanotechnology. Aims and Objectives: The present study reports the synthesis of silver nano...
Effect of Pterocarpus marsupium in animal model of high carbohydrate diet-induced metabolic syndrome
Background: Metabolic syndrome (MS) is a group of interconnected disorder linked to obesity, insulin resistance hypertension, and dyslipidemia. It is a risk factor for the development of Type II diabetes and cardiovascul...
Assessment of cognitive function in patients with alcohol dependence: A cross-sectional study
Background: This study aimed to evaluate cognition in patients with alcohol dependence. During the past decade, there has been an increasing interest in the evaluation of cognitive function in substance use disorders. Su...
Evaluation of anticonvulsant activity of ethanolic extract of leaves of Ocimum sanctum (tulsi) in albino rats
Background: Epilepsy is a chronic neurological disorder. Ocimum sanctum (OS) (tulsi) has analgesic, anticancer, antiasthmatic, antidiabetic, antifertility, hepatoprotective, hypotensive, hypolipidemic, anti-inflammatory,...