Comparison of Nonshivering Thermogenesis Induced by Norepinephrine Stress in Tree Shrews
Journal Title: Журнал ÑтреÑÑ-физиологии и биохимии - Year 2013, Vol 9, Issue 4
Abstract
Nonshivering thermogenesis (NST) is an important thermogenic mechanism for small mammals. Quantitative measurement of NST is usually stimulated by injection of norepinephrine. The injection dosage of norepinephrine (NE) is critical for eliciting the maximum NST. Three empirical equations of NE dosages were often referenced in previous studies: (1) NE (mg / kg)= 2.53W[sup]-0.4[/sup]; (2) NE(mg/kg) = 3.3W[sup]-0.458[/sup] and (3) NE(mg/kg)= 6.6W[sup]-0.458[/sup]. In the present study , we used tree shrews ([i]Tupaia[/i] [i]belangeri[/i]) as experiment subjects to test the effects of the three dosages of NE on NST. Results showed that all the three dosages of NE could induce the maximum NST for [i]T. belangeri[/i]. No significant differences were found in NST among groups and the NST was respectively 2.63±0.12 (formula 1), 2.66±0. 11 (formula 2) and 2.78±0.15 (formula 3). However, when injected with NE dosage from formula 3, the increase of body temperatures was significantly higher than the other two NE dosages (increased 1.5±0. 1 [sup]o[/sup]C (formula 3), 0.8±0. 2 [sup]o[/sup]C (formula 2), and 0.6±0. 1 [sup]o[/sup]C (formula 1), respectively). In order to prevent the death because of hyperthermia, formula 1 or 2 is recommended to be used.
Authors and Affiliations
Wan-long Zhu, Di Zhang, Jia Zheng, Lin Zhang, Jin-hu Liu, Jin Cheng, Zheng-kun Wang
Keywords
Related Articles
- EP ID EP120703
- DOI -
- Views 119
- Downloads 0
Evaluation of the Effect of Oxidative Stress on Roots of Red Beet (Beta vulgaris L.)
In the present investigation it was studied the effect of oxidative stress on root of red beet. The degree of stress exposure was assessed at various levels: in tissues of roots (conductometric method), on isolated vacuo...
Drought Tolerance Induced by Foliar Application of Abscisic Acid and Sulfonamide Compounds in Tomato
The effects of exogenous abscisic acid and two sulfonamide compounds: Sulfacetamide and Sulfasalazine were studied on tolerance of tomato (Lycopersicon esculentum Mill. cv. Super chief) under drought stress and compared...
Effects of photoperiod on body mass, thermogenesis and body composition in Eothenomys miletus during cold exposure
Many small mammals respond to seasonal changes in photoperiod by altering body mass and adiposity. These animals may provide valuable models for understanding the regulation of energy balance. In present study, we examin...
Tissue specific responses alter the biomass accumulation in wheat under gradual and sudden salt stress
Salinity is one the major limiting environmental factors which has negative side effects on crop production. The purpose of this study was to investigate the differences between the gradual and sudden salt stress effects...
Biochemical Response of Glycine max (L.) Merr. to Cobalt and Lead stress
[b]Background:[/b] Heavy metal pollution of soil has become a global concern, largely due to the fact that the heavy metals accumulated in plants may either directly or indirectly find their way into animals and human be...