CYTOTOXIC STUDIES OF 3-(1-BENZOFURAN-2-YL)-5- (SUBSTITUTED ARYL) ISOXAZOLE
Journal Title: International Journal of Pharmaceutical Applications - Year 2011, Vol 2, Issue 1
Abstract
The 3-(1-benzofuran-2-yl)-5-(substituted phenyl) isoxazole, I1-I7 was evaluated for in vitro cytotoxic activity on HeLa cell lines at the minimum seven concentrations at two fold dilutions. Amongst all the compound I4 has shown good activity. While, Compound I5 has shown moderate activity. The remaining tested compounds were not cytotoxic effect on tested cell lines
Authors and Affiliations
Rajeshkumar Sahu , Jaishree V , B. Ramesh , Anand Mahalwar , Sachin L. Patil
CYTOTOXIC STUDIES OF 3-(1-BENZOFURAN-2-YL)-5- (SUBSTITUTED ARYL) ISOXAZOLE
The 3-(1-benzofuran-2-yl)-5-(substituted phenyl) isoxazole, I1-I7 was evaluated for in vitro cytotoxic activity on HeLa cell lines at the minimum seven concentrations at two fold dilutions. Amongst all the compoun...
ANTIBACTERIAL TARGETS IN PSEUDOMONAS AERUGINOSA
Pseudomonas aeruginosa is a deadly opportunistic pathogen. It causes life-threatening infections in individuals with compromised immune systems, such as cancer patients undergoing chemotherapy or patients with cy...
EFFECT OF GLYCOWITHANOLIDES ON SIALIC ACID CONTENT IN SALIVARY GLANDS OF D-GALACTOSE INDUCED AGING MICE
The study was undertaken to find out effect of glycowithanolides (WSG) extracted from Withania somnifera leaves on sialic acid content in submandibular and sublingual salivary glands of D-galactose induced aging...
STUDY THE EFFECT OF PLANT EXTRACT ON ENDOPARASITE
The present research studies detail anthelmintic activity of Drynaria quercifolia (L) J. Sm., a medicinal plant on Capra hircus (L). The present fern spp. was authenticated through taxonomic studies. Study also in...