STUDY THE EFFECT OF PLANT EXTRACT ON ENDOPARASITE
Journal Title: International Journal of Pharmaceutical Applications - Year 2011, Vol 2, Issue 4
Abstract
The present research studies detail anthelmintic activity of Drynaria quercifolia (L) J. Sm., a medicinal plant on Capra hircus (L). The present fern spp. was authenticated through taxonomic studies. Study also involved survey of endoparasites to understand prevalence of major endoparasites in different agroclimatic zones of Western Maharashtra, India. To facilitate invitro research studies, new methods have been experimentally tested and reported for indicating the efficacy of D. quercifolia (L) J. Sm., extracts on helminthes. Survey conducted for assessing prevalence of endoparasites in goat’s confirmed the prevalence of endoparasites (Nematodirus spp., Trichuris spp., Eimeria spp. and Haemonchus contortus) under Western Maharashtra condition of India. H. contortus was most prominent; therefore further invitro and invivo studies were restricted to these species as representative parasites in C. hircus for studying the anthelmintic activities of D. quercifolia. The present investigation may form the basis for development of knowledge and formulation of drugs for preventing the endoparasites infection in C. hircus and can be used as a model for developing approach for livestock health improvement. Considering this usefulness of the same plant product having multipurpose medicinal values, D. quercifolia rhizome may be used as ecofriendly herbal low cost remedy available among the village people, a remedy for perennial problem of infections in C. hircus and to prevent the losses thereof. Present work also opens up paths to many more studies for further exploration, for example- the extracts to be tested against spectrum of vectors and pathogens, active compounds to be isolated which will lead this research in finding active drug molecules.
Authors and Affiliations
Marathe R. R. , , Patil V. C , Muley S. M , Krishna Kumar Singh , Suresh Gokhale
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