Dynamics of Combined Oral Contraceptive: A Study of Some Haematological Parameters in Female Wistar Rats
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 9
Abstract
Contraception is the intentional prevention of fertilization from taking place through the use of various devices, sexual practices, barrier methods and hormonal contraception. Contraception is as old as human existence.. Oral contraceptives are a simple form of contraception used by women worldwide. The oral contraceptive is one of the greatest and most influential developments of the twentieth century.Haematopoiesis is the process by which all lineages of blood cells are generated in a hierarchical and stepwise manner from immature cells present in the bone marrow (BM)’ and subsequently released into circulating blood and peripheral organs for further maturation steps and/or effector function.Several haemorheological and haemostatic parameters has been associated closely with hormone replacement therapy. Such parameters include blood viscosity, plasma viscosity, haematocrit value, fibrinogen level and fibrinolytic activity. This research priority included efforts to discover the effect of COC (DUOFEM) on haematological parameters.
Authors and Affiliations
Toryila J. E1 , Amadi K2 , Odeh S. O2 , Adelaiye A. B1 ,Egesie U. G. 2Achie1 l N
Keywords
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