EPITHELIOID TROPHOBLASTIC TUMOUR: A RARE CASE WITH AN UNUSUAL PRESENTATION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 57
Abstract
Here in we report a rare case of epithelioid trophoblastic tumour with a rare clinical presentation. Commonly, ETT presents with abnormal vaginal bleeding or lung metastases. Our case was a 22-year-old lady, Para 2, Live 2, Last Child Birth was one year with History of amenorrhoea presented with abdominal pain on and off, and initial Ultrasonogram had fluid in Pouch of Douglas with elevated beta HCG levels-421.4 miu/mL. She was diagnosed as ectopic pregnancy. Laparotomy was done, which turned out to be negative. So patient was referred to our institute with abdominal distension and ascites. MRI showed heterogeneously enhancing lesion in myometrium, lateral wall of cervix and anterior wall of vagina with gross ascites. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was done. Microscopy showed a neoplasm composed of round to polygonal intermediate trophoblastic cell arranged in sheets and clusters, the cells with high-grade nucleus and mitotic activity. Tumour cells were seen infiltrating the myometrium with extensive areas of necroses. Immunohistochemistry showed P63 strong positive, inhibin +ve, EMA +VE, PLAP +VE, beta HCG and Desmin were negative. Histology and IHC were consistent with Epithelioid trophoblastic tumour. This case shows that ETT can also present as abdominal pain with elevated beta HCG and mimic an ectopic pregnancy. The case is presented for its challenging diagnostic dilemma and rare presentation as abdominal distension and ascites.
Authors and Affiliations
Jayanandhini , Kanchana Padmanaba
Keywords
Related Articles
- EP ID EP144181
- DOI 10.14260/jemds/2016/908
- Views 89
- Downloads 0
PATTERN OF SUICIDAL DEATHS- A REVIEW OF AUTOPSY CASES IN 2015 AND 2016
BACKGROUND Suicide is high in societies that are socially isolated, mobile and disorganised. Differences exist in countries in the most common means of suicide depending on the availability of various methods. Different...
SONOGRAPHIC CORRELATION OF CAROTID INTIMA MEDIA THICKNESS AND HEPATIC ECHOTEXTURE WITH SERUM LIPID PROFILE
BACKGROUND Today ultrasound has emerged as a powerful diagnostic medical tool as it is cost effective, widely available and there is no risk of radiation. Driven by an increasing public awareness, as well as advances in...
A COMPARATIVE STUDY OF ANTHROPOMETRIC PARAMETERS OF INFANTS &THEIR MOTHERS IN WESTERN RAJASTHAN POPULATION
[b]AIMS AND OBJECTIVE[/b]: Growth of whole body is an integrated & composite process. Pregnancy is one of the most critical and unique period in a women’s life. The aim of present study is to determine the...
A RETROSPECTIVE STUDY OF THE IMPACT OF RADIATION FRACTIONATION ON PAINFUL BONE METASTASIS
BACKGROUND Bone metastasis and bone pain are most detrimental to the life of cancer patients. There is a significant discrepancy between the physician estimate of pain and the pain level reported by the patient. We wante...
TO COMPARE THE EFFICACY AND SAFETY OF THIOCOLCHICOSIDE AND CHLORZOXAZONE IN MUSCLE SPASM ASSOCIATED WITH LOW BACK PAIN
BACKGROUND Higher incidence of LBP is reported in Indian population in younger patients due to occupational exposure and lack of exercise. In general, LBP is managed with the short-term use of Non-Steroidal Anti-Inflamma...