EPITHELIOID TROPHOBLASTIC TUMOUR: A RARE CASE WITH AN UNUSUAL PRESENTATION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 57
Abstract
Here in we report a rare case of epithelioid trophoblastic tumour with a rare clinical presentation. Commonly, ETT presents with abnormal vaginal bleeding or lung metastases. Our case was a 22-year-old lady, Para 2, Live 2, Last Child Birth was one year with History of amenorrhoea presented with abdominal pain on and off, and initial Ultrasonogram had fluid in Pouch of Douglas with elevated beta HCG levels-421.4 miu/mL. She was diagnosed as ectopic pregnancy. Laparotomy was done, which turned out to be negative. So patient was referred to our institute with abdominal distension and ascites. MRI showed heterogeneously enhancing lesion in myometrium, lateral wall of cervix and anterior wall of vagina with gross ascites. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was done. Microscopy showed a neoplasm composed of round to polygonal intermediate trophoblastic cell arranged in sheets and clusters, the cells with high-grade nucleus and mitotic activity. Tumour cells were seen infiltrating the myometrium with extensive areas of necroses. Immunohistochemistry showed P63 strong positive, inhibin +ve, EMA +VE, PLAP +VE, beta HCG and Desmin were negative. Histology and IHC were consistent with Epithelioid trophoblastic tumour. This case shows that ETT can also present as abdominal pain with elevated beta HCG and mimic an ectopic pregnancy. The case is presented for its challenging diagnostic dilemma and rare presentation as abdominal distension and ascites.
Authors and Affiliations
Jayanandhini , Kanchana Padmanaba
Keywords
Related Articles
- EP ID EP144181
- DOI 10.14260/jemds/2016/908
- Views 88
- Downloads 0
A SERO-EPIDEMIOLOGICAL STUDY OF HERPES SIMPLEX VIRUS- 2 ANTIBODIES AMONG PATIENTS WITH SEXUALLY TRANSMITTED INFECTIONS
BACKGROUND Herpes genitalis (HG) is a sexually transmitted infection of great public health importance. HSV-2 is the major cause of the infection in more than 80% of such cases. Many patients with other sexually transmit...
VISA AMONGST MRSA ISOLATES IN A TERTIARY CARE HOSPITAL IN MANIPUR
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital acquired and community-acquired infections. MRSA isolates are important for their resistance to many commonly used antibiotics. V...
A STUDY ON THE AETIOLOGICAL PROFILE OF PAIN AROUND SHOULDER AMONG PATIENTS ATTENDING PHYSICAL MEDICINE AND REHABILITATION DEPARTMENT OF A TERTIARY CARE CENTRE
ACKGROUND Pain around the shoulder is one of the most common regional musculoskeletal conditions seeking medical advice. It has a lifetime prevalence of up to 70% and this seems to be increasing in incidence. The diagnos...
A DESCRIPTIVE STUDY ON PATIENTS OF CARCINOMA LARYNX ATTENDING TERTIARY CARE CENTRES IN HYDERABAD, TELANGANA
BACKGROUND Laryngeal cancer is the eleventh most common cancer in men worldwide, but is relatively uncommon in women. Cancer larynx constitutes 2.63% of all body cancers in India. Tobacco smoking and alcohol are the majo...
STUDY OF AETIOLOGY AND CLINICAL OUTCOMES IN COMA PATIENTS WITH NORMAL BRAIN CT SCAN
BACKGROUND Coma is one of the common problems with which patients get admitted into the emergency department. Coma is a state of unconsciousness from which the patient cannot be awakened; it indicates either structural o...