HYDROLETHALUS SYNDROME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 24
Abstract
Hydrolethalus Syndrome (HLS) is a rare lethal genetic syndrome, recognized as a consequence of a study on Meckle syndrome in Finland .1 HLS is characterized by multiple developmental defects of fetus which include fetal hydrocephalus, agenesis of corpus callosum, absent midline structures of brain, Cleft lip and cleft palate, defective lobulation of lungs, micrognathia and very characteristic abnormality of polydactyly. About 80% of patients have polydactyly, in hands it is postaxial and preaxial in feet with duplicated big toe. A highly characteristic hallux duplex is seen in almost no other situation .2 Club feet is also common.
Authors and Affiliations
Aradhana Kankane, Arvind Kankane, Tarun Chandra
Keywords
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- EP ID EP122672
- DOI 10.14260/jemds/862
- Views 88
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