In vitro antimalarial and xanthine oxidase inhibition of 2- Aminoanthraquinone
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2016, Vol 29, Issue 2
Abstract
In the present research study 2-Aminoanthraquinone were scrutinized for their antimalarial and Xanthine oxidase inhibitor potential. It demonstrated marked concentration dependent antimalarial activity with maximum effect of 89.06% and with IC50 of 34.17 µM. Regarding Xanthine oxidase inhibitor activity, it evoked significant effect with 57.45% activity with IC50 value of 81.57.19µM. In conclusion, 2-Aminoanthraquinone showed potent antimalarial and xanthine oxidase inhibitory activity.
Authors and Affiliations
Abdur Rauf , Rehan Khan , Haroon Khan , Noor Jehan , Mohammad Akram, , Zarka Ahmad , Naveed Muhammad , Umar Farooq , Ajmal Khan
Keywords
Related Articles
- EP ID EP90687
- DOI -
- Views 102
- Downloads 0
Chemical composition, in vitro cytotoxicity and anti-free radical properties of six extracts from Lebanese Trigonella berythea Boiss.
This study represents an original work aimed to recognize the main constitution of Trigonella berythea. The total phenolic content and total flavonoid content of leaves and stems of T. berythea have been estimated....
Molecular basis of antibacterial activities in extracts of Eucommia ulmoides wood
As one of the famous medicinal plants in China, the bark of Eucommia ulmoides is considered as the important traditional Chinese medicine. However, the constituents of Eucommia ulmoides wood isn’t used effectively....
Effectiveness and Safety of a 10mg Warfarin Initiation Nomogram in Asian Population
Anticoagulant responses to warfarin vary among patients, based on genetic factors, diet, concomitant medications, and disease state. We evaluated the effectiveness and safety of a 10mg warfarin initiation nomogram...
Antioxidant activity of bulbs and aerial parts of Crocus caspius, impact of extraction methods
Crocus genus (Iridaceae) is comprises approximately 80 species. In this study in vitro antioxidant activities of extracts from C. caspius bulbs and aerial parts were investigated. Ultrasonically assisted extraction...
Synthesis, characterization and enzyme inhibition study of O-substituted derivatives of chlorinated coumarin
Abstract: Coumarins have much importance in dyes, drugs, perfumes and pesticides. In the demonstrated research work, a benignant series of chlorinated coumarins was synthesized and screened against different enzyme...