In vitro antimalarial and xanthine oxidase inhibition of 2- Aminoanthraquinone
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2016, Vol 29, Issue 2
Abstract
In the present research study 2-Aminoanthraquinone were scrutinized for their antimalarial and Xanthine oxidase inhibitor potential. It demonstrated marked concentration dependent antimalarial activity with maximum effect of 89.06% and with IC50 of 34.17 µM. Regarding Xanthine oxidase inhibitor activity, it evoked significant effect with 57.45% activity with IC50 value of 81.57.19µM. In conclusion, 2-Aminoanthraquinone showed potent antimalarial and xanthine oxidase inhibitory activity.
Authors and Affiliations
Abdur Rauf , Rehan Khan , Haroon Khan , Noor Jehan , Mohammad Akram, , Zarka Ahmad , Naveed Muhammad , Umar Farooq , Ajmal Khan
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