INTESTINAL PARASITES IN PATIENTS HAVING HAEMATOLOGICAL MALIGNANCIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 31
Abstract
BACKGROUND Haematological malignancies like leukaemia, lymphoma and myeloma originate in the bone marrow, lymph nodes which may be acute and chronic. These patients receive immunosuppressive agents, which put them at increased risk of infections, especially due to intestinal parasites. Parasitic infections if not diagnosed early may give rise to morbidity and mortality, more so if these infections remain asymptomatic, such patients pose a threat to others in the community. Hence, early diagnosis of intestinal parasitic infections is mandatory. AIMS To determine the prevalence of intestinal parasitic infections in patients having haematological malignancy. SETTINGS AND DESIGN 125 patients in the age group of 3 to 60 years diagnosed to have haematological malignancies receiving chemotherapy were recruited for the present study and were instructed to bring three fresh stool specimens on non-consecutive days. The study was carried out for one year at a tertiary care multi-speciality teaching institute. MATERIAL AND METHODS Gross and microscopic examination, concentration technique of Formol ether sedimentation and saturated common salt solution were used. Permanent staining technique using Trichrome stain and Modified acid fast staining technique were performed on all the stool samples. RESULTS Overall prevalence of intestinal parasites detected was 54.4%. Intestinal parasites were detected in 68.75%, 54.85%, 46.88% and 46.6% of patients having Acute Lymphoblastic Leukaemia (ALL), Acute Myeloid Leukaemia (AML), Multiple myeloma (MM) and Lymphoma respectively. Protozoan parasites, Giardia lamblia were predominant in the list. Mixed infections were not seen. Coccidian intestinal parasites were not detected. CONCLUSION Screening of stool specimens of patients having haematological malignancies at regular interval to detect the presence of intestinal parasites should be made a mandatory practice.
Authors and Affiliations
Sneha , Avani , Shivani , Preeti
Keywords
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- EP ID EP164736
- DOI 10.14260/jemds/2016/380
- Views 82
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