ISOMETRIC HANDGRIP: A TOOL TO EVALUATE SYMPATHETIC DOMINANCE IN OFF SPRINGS OF HYPERTENSIVE PARENTS AND ROLE OF DIET IN THEM
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 20
Abstract
BACKGROUND Genetic factors likely play some role in causing a high blood pressure. About 30% of patients with primary hypertension have genetic predisposition. It is a well-documented fact that sympathetic dominance increases heart rate and blood pressure and the same has been observed in young normotensive off springs of hypertensive parents. AIM Aim of the present study was to evaluate pulse and blood pressure responses to isometric hand grip in children of hypertensives and non-hypertensives. METHODS The present study was conducted in 120 subjects, 59 of whom had a positive family history and 61 had no family history of hypertension. Isometric hand grip as a sympathetic test was carried out in both the groups following measurement of resting pulse and blood pressure. Five minutes following isometric hand grip pulse and blood pressure recordings were taken. Children of hypertensives were further divided into vegetarian and non-vegetarian group and the same parameters were compared in them before, during and after conducting isometric handgrip. RESULTS Results were tabulated and analysed using Independent ‘t’ test. P value <0.05 was considered as significant. A statistically significant increase in pulse and blood pressure values were obtained in children of hypertensives at rest during and five minutes after performing isometric handgrip. Findings are suggestive of an increased sympathetic dominance in children of hypertensives. Higher pulse and blood pressure values in resting state, during and after the procedure were obtained in non-vegetarian group of hypertensive children. However, these values were not statistically significant. CONCLUSION The present study suggests that healthy children of hypertensive parents do have a sympathetic dominance when compared to healthy children of non-hypertensive parents.
Authors and Affiliations
Vishrutha , Arati Rao, Harini , Vandana
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