LIQUID CRYSTAL AS COLON TARGETED DRUG DELIVERY: A OVERVIEW
Journal Title: Int J of Pharm Rev& Res - Year 2016, Vol 6, Issue 1
Abstract
ABSTRACT Liquid crystals are matter in a state that has properties between those of conventional liquid and those of solid crystals. It is basically a thermodynamic stable phase .The colon is a site where both local and systemic delivery of drugs can take place. Local delivery allows topical treatment of inflammatory bowel disease. However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the systemic side effects. Liquid crystals have generated considerable alertness over the years as a potential drug delivery vehicle. The drugs to be used as CTTDS are firstly brought into the LCs stage, then it is coated in the form of microspheres with the help of Eudragit® S100 which is an anionic copolymers based on methacrylic acid and methyl methacrylate . This review article summarizes about liquid crystals and their use as Colon targeted drug delivery system. Key words: Colon drug delivery system, Liquid crystals, Inflammatory bowel disease, Eudragit.
Authors and Affiliations
Sompriya Chatterjee*
Keywords
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