NANOSUSPENSION OF A DRUG AND ITS BIOLOGICAL ACTIVITYA REVIEW
Journal Title: Int J of Pharm Rev& Res - Year 2016, Vol 6, Issue 2
Abstract
ABSTRACT With the modern technologies, a large number of drugs have been discovered which have better efficiency but their clinical applications are restricted due to poor solubility. Nearly 40% of the drugs have poor solubility. Poor water solubility has become a leading challenge for formulation of these compounds. Poor solubility is generally associated with poor bioavailability. Nanosuspension has the potential to overcome this issue. This review article outlines various techniques involved for preparation of nanosuspension and the enhancement of biological activities of drug when formulated into nanosuspension. Key words: Nanosuspension, Solubility of drug, Dissolution rate
Authors and Affiliations
Sharamol AR, Smitha K Nair, Anish John, K. Krishnakumar, Dineshkumar B*
Keywords
Related Articles
- EP ID EP90766
- DOI -
- Views 189
- Downloads 0
CHRONOMODULATED DRUG DELIVERY SYSTEM: A REVIEW
In this review, the concepts of biological rhythms, chronobiology, chronopharmacology, and chronotherapy for various diseases have been discussed. Chronopharmaceutical Drug Delivery Systems (ChrDDS) is novel system which...
PRESCRIBING PATTERN OF DRUGS IN PEDIATRIC WARDS AT A TERTIARY CARE TEACHING HOSPITAL
Pediatrics differs from adult medicine in many respects. Inappropriate prescribing is a recognized worldwide problem of the health care delivery system. Antibiotics are the widely used drugs in modern medical care. A pro...
SPECTROPHOTOMETRIC ESTIMATION OF ZIDOVUDINE IN BULK AND TABLET DOSAGE FORM
A simple, rapid and economical spectrophotometric was developed for the estimation of zidovudine in bulk and tablet dosage forms. The results obtained were found to be good and sensitive. The method was validated and was...
IN VITRO STUDY ON THROMBOLYTIC ACTIVITY OF HYDROALCOHOLIC EXTRACT OF VALERIANA JATAMANSI AND ORIGANUM VULGARE LEAVES
The present study was investigated to find out the thrombolytic activity of hydroalcoholic extract of Valeriana Jatamansi and Origanum Vulgare leaves by using in vitro method along with streptokinase as a standard. The s...
A SILENT CRISIS: RECENT DRUG DISCOVERY IN CANCER RESEARCH
This article represents the recent drug discovery in cancer research. Cancer is a term which describes a group of perhaps 120 different diseases which share some broad similarities. The body is made up of hundreds of mil...