SPECTROPHOTOMETRIC ESTIMATION OF ZIDOVUDINE IN BULK AND TABLET DOSAGE FORM
Journal Title: Int J of Pharm Rev& Res - Year 2012, Vol 2, Issue 2
Abstract
A simple, rapid and economical spectrophotometric was developed for the estimation of zidovudine in bulk and tablet dosage forms. The results obtained were found to be good and sensitive. The method was validated and was found to be accurate, precise and sensitive. The λmax of the zidovudine was found to be at 266nm. Methanol used as a diluent. The method was found linear over the range of 5-25 μg per ml for zidovudine. The proposed method was validated as per the ICH and USP guidelines. The proposed method can be extended to different quality control labs and research and educational institutes for routine analysis of Zidovudine in bulk and dosage forms
Authors and Affiliations
G. Balammal , P. Habeeb khan , P. Jayachandra Reddy
Keywords
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