PNEUMOCYSTIS JIROVECII PNEUMONIA: PREVALENCE IN HOSPITALISED PATIENTS, A STUDY CONDUCTED IN A TERTIARY CENTRE IN PUNJAB
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 32
Abstract
BACKGROUND Pneumocystis jirovecii is a pathogen causing a life-threatening infection, Pneumocystis Pneumonia (PCP) in T helper cell deficient hosts. METHODS A retrospective analysis was done from 6th April 2012 to 11th September 2015. The clinical data of the positive patients for PCP by Silver Methenamine Staining of the samples were collected. CD4 counts were done for the HIV positive patients. RESULTS A total of 486 samples were sent to the Microbiology Lab during this period for Silver Methenamine Staining. Among the patients, 13 (35.15%) were diagnosed cases of HIV; 9 were Stage IV AIDS and all of these patients had CD4 counts less than 200/µL. Fungal pneumonia was found to be a significant comorbidity in these patients and is of particular significance due to the diagnostic dilemma it can cause, since the radiological and physiological changes in both fungal and pneumocystis pneumonia are similar. CONCLUSION There should be a high index of suspicion for pneumocystis pneumonia in susceptible patients who show signs of atypical pneumonia and who do not respond to treatment with antibiotics or antifungals.
Authors and Affiliations
Dilip , Aroma , Eshani , Vipin Alexander
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