SONOGRAPHIC GRADING OF RENAL CORTICAL ECHOGENICITY AND RAISED SERUM CREATININE IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 38
Abstract
BACKGROUND Chronic Kidney Disease (CKD) is a worldwide public health problem and the world’s 12th commonest cause of mortality and 17th cause of morbidity. The approximate prevalence of CKD in India is 800 with an incidence of about 150-200 per million population. The most common cause of CKD is diabetic nephropathy. PURPOSE OF STUDY The purpose was to study various renal sonographic changes in patients with chronic kidney disease and to correlate renal length, parenchymal thickness, cortical thickness and echogenicity of the kidney with serum creatinine levels. MATERIAL AND METHODS The study was conducted on hundred patients in the Department of Radiodiagnosis and Imaging, Government Medical College, Amritsar, from August 2013 to October 2015. Patients were subjected to sonographic examination on Philips Envisor C Ultrasound machine/Toshiba ultrasound machine model–SSA. 510A/Esaote ultrasound machines using curvilinear probe of 3.5 MHz - 5 MHz or linear high frequency probe 7-12 MHz. Ultrasound of kidneys for renal length, parenchymal thickness, cortical thickness and cortical echogenicity was performed. The mean values of both kidneys were calculated from length, parenchymal thickness and cortical echogenicity. These parameters were compared with serum creatinine. Statistical analysis was performed using one-way ANOVA. RESULTS AND CONCLUSIONS The grade of renal disease was determined by cortical echogenicity with Grade 1 mild form, Grade 2 moderate and Grade 3 severe form and Grade 4 as end-stage renal disease. The mean serum creatinine was 2.87 mg/dL for Grade 1, 3.27 mg/dL for Grade 2, 4.3 mg/dL for Grade 3 and 5.8 mg/dL for Grade 4. No correlation was observed between renal length, parenchymal thickness and cortical thickness with serum creatinine levels. The grading of renal echogenicity on sonography correlated well with serum creatinine in CKD than any other sonographic parameters with a statistically significant positive correlation (P <0.001).
Authors and Affiliations
Arvinder , Kamlesh , Ramesh , Mayur
Keywords
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- EP ID EP159607
- DOI 10.14260/jemds/2016/530
- Views 64
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