STUDY OF FOSFOMYCIN TROMETAMOL IN ACUTE LOWER URINARY TRACT INFECTIONS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 31
Abstract
OBJECTIVES To evaluate the efficacy of single oral dose of Fosfomycin Trometamol (FT) in patients of uncomplicated lower urinary tract infections. METHODS One hundred women between 18-65 years’ age group with uncomplicated Urinary Tract Infection (UTI) with culture positive for E. coli and Enterococcus were enrolled in this prospective study. Patients with culture positive for E. coli and Enterococcus and with in-vitro susceptibility to Fosfomycin Trometamol (FT) as tested by Kirby-Bauer disc diffusion method were given single oral dose of Fosfomycin trometamol, i.e. 3 g. These patients were followed up for clinical and bacteriological cure and any adverse effects. RESULTS The incidence of E. coli infection was 86% and Enterococcus infection was 14%; 78% of E. coli isolates were susceptible to FT with 22% being resistant; 86% of Enterococcus isolates were susceptible to FT with 14% being resistant. Incidence of adverse effects of FT was only 2%. CONCLUSIONS Fosfomycin trometamol might be considered as a promising single dose oral antibiotic for uncomplicated UTI due to E. coli and Enterococcus spp
Authors and Affiliations
Preetkamal , Kanwardeep , Prabjot
Keywords
Related Articles
- EP ID EP101735
- DOI 10.14260/jemds/2016/388
- Views 82
- Downloads 0
PREVALENCE OF ANAEMIA IN PREGNANT WOMEN- A SINGLE INSTITUTION STUDY WITH SPECIAL REFERENCE TO RURAL AREA OF NORTH INDIA
BACKGROUND Anaemia is the commonest medical disorder in pregnancy. In developing countries, anaemia contributes to 40-60% of all maternal deaths directly or indirectly.1,2 In India 16% of all maternal deaths are directly...
AN UNUSUAL CASE OF COPPER-T INTRAUTERINE CONTRACEPTIVE DEVICE IN THE URINARY BLADDER.
Intrauterine contraceptive device (IUCD) is the best spacing method of contraception widely practiced all over the world. Although it is widely accepted and a safe procedure of insertion is practiced a rare cha...
CYTOLOGIC PATTERNS OF LUNG CANCER
BACKGROUND Lung cancer is the most common cancer in the world today and the most common cause of cancer death in developing countries. The symptoms of lung cancer are often subtle and the diagnosis in about 70% of cases...
POST CHOLECYSTECTOMY AND THE DYSPEPTIC PATIENT TO IDENTIFYING THE APPROPRIATENESS OF OPERATIVE INTERVENTION IN CHENGALPATTU MEDICAL COLLEGE
BACKGROUND Dyspepsia is defined by the discomfort or pain localised in the upper abdomen. This pain is common with a prevalence of forty to sixty percent in the general population. But often 55% of patients do not have a...
CLINICO-AETIOLOGICAL PROFILE OF NEONATAL SEIZURES AND THEIR OUTCOMES IN A TERTIARY CARE HOSPITAL
BACKGROUND Neonatal seizures defined as seizures occurring in first 28 days of life are one of the most common morbidity factors of admission in NICU. Incidence is 1.5 - 14/ 1000 neonates. Seizures often signify serious...