STUDY OF FOSFOMYCIN TROMETAMOL IN ACUTE LOWER URINARY TRACT INFECTIONS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 31
Abstract
OBJECTIVES To evaluate the efficacy of single oral dose of Fosfomycin Trometamol (FT) in patients of uncomplicated lower urinary tract infections. METHODS One hundred women between 18-65 years’ age group with uncomplicated Urinary Tract Infection (UTI) with culture positive for E. coli and Enterococcus were enrolled in this prospective study. Patients with culture positive for E. coli and Enterococcus and with in-vitro susceptibility to Fosfomycin Trometamol (FT) as tested by Kirby-Bauer disc diffusion method were given single oral dose of Fosfomycin trometamol, i.e. 3 g. These patients were followed up for clinical and bacteriological cure and any adverse effects. RESULTS The incidence of E. coli infection was 86% and Enterococcus infection was 14%; 78% of E. coli isolates were susceptible to FT with 22% being resistant; 86% of Enterococcus isolates were susceptible to FT with 14% being resistant. Incidence of adverse effects of FT was only 2%. CONCLUSIONS Fosfomycin trometamol might be considered as a promising single dose oral antibiotic for uncomplicated UTI due to E. coli and Enterococcus spp
Authors and Affiliations
Preetkamal , Kanwardeep , Prabjot
Keywords
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- EP ID EP101735
- DOI 10.14260/jemds/2016/388
- Views 79
- Downloads 0
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