STUDY OF GENITAL TUBERCULOSIS IN INFERTILE WOMEN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 50
Abstract
AIM To determine the incidence of female Genital Tuberculosis (GTB) and to analyse clinicopathological features for GTB and comparison of Polymerase Chain Reaction (PCR), Acid Fast Bacillus (AFB) staining and Histopathology (HPR). STUDY SETTING A prospective study conducted on 50 infertile patients in the Department of Obstetrics and Gynaecology at Krishna Hospital, Karad, for a period of 2 years between December 2013 and December 2015. METHODS Patients were investigated for the presence of Mycobacterium Tuberculosis (MTB) on samples collected by endometrial curettage by PCR, AFB and HPR. Additional tests like Hysterosalpingography (HSG) Laparoscopic chromopertubation and hysteroscopy were performed if not done earlier. RESULT PCR demonstrated MTB DNA in 9 patients, and 2 were positive with AFB and HPR. Within positive patients HSG findings were suggestive of TB in 3 cases and laparoscopy in 5 cases and hysteroscopy in 4 cases. Two MTB PCR positive patients conceived spontaneously after 6 months of anti-tubercular treatment. CONCLUSION Genital tuberculosis is a diagnostic challenge if untreated it is chronic, progressive and destructive disease. Early diagnosis is crucial because once the infection damages the tubes, reverting tubal patency is very difficult. Molecular tests like DNA PCR have enabled us to detect the organism in its latent stage and initiation of treatment early in the disease can prevent many irreversible changes in the female genital tract.
Authors and Affiliations
Shrikant , Sanjay Patil, Anjali , Yamini , Kshirsagar
Keywords
Related Articles
- EP ID EP138879
- DOI 10.14260/jemds/2016/741
- Views 104
- Downloads 0
CUMULATIVE IMPACT OF YOGA PRACTICE ON QUALITY OF LIFE
The present study was conducted with two main objectives. First it aims to experiment whether the ancient system of yoga can bring about change in the quality of life of its practitioners. The second objective...
HER-2/NEU EXPRESSION IN STOMACH AND GASTRO-OESOPHAGEAL JUNCTION CARCINOMA IN ENDOSCOPIC BIOPSY SPECIMENS
BACKGROUND Prognosis of patients with advanced inoperable carcinoma of stomach and gastro-oesophageal junction remains dismal with palliative chemotherapy. In spite of extensive efforts, the five-year survival rate of th...
A RARE PRESENTATION OF CEREBROVASCULAR INSUFFICIENCY
Locked in syndrome refers to a neurological condition associated with infarction of the ventral pons. The syndrome is manifested by quadriplegia, lower cranial nerve paralysis and mutism with preservation of onl...
A CLINICAL STUDY ON PALMAR DERMATOGLYPHICS IN PSORIASIS
A CLINICAL STUDY ON PALMAR DERMATOGLYPHICS IN PSORIASIS Aswathy Umesh1, Priya Ashok2, Joan Felicita Samson3 1Junior Resident, Department of Dermatology & Venereology, Government Medical College, Trivandrum. 2Assistant Pr...
FIBROUS DYSPLASIA OF SPHENOID BONE IN A 4-YEAR-OLD WITH UNILATERAL PROPTOSIS
A 4-year-old male child presented to the Eye OPD with complaints of protrusion of left eye since 2 months (Fig. 1). The protrusion was gradually progressive and the patient also complained of associated headache. There w...