STUDY ON SEPSIS-CLINICAL, BIOCHEMICAL PROFILE AND CORRELATION WITH BLOOD CULTURE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 56
Abstract
[b] AIM[/b]: To study the pattern and outcome of the patients with sepsis. [b]OBJECTIVE[/b]: To find the occurrence of positive blood culture among the different grades of sepsis and assess the type of organ dysfunction commonly encountered. [b]MATERIAL AND METHOD[/b]: The present study is a cross sectional study, conducted over the patient of sepsis, who are admitted JAH Group of hospital, Gwalior, M. P. Data was collected from 100 patients. Blood sample for bacterial culture/sensitivity were collected and sent soon after a diagnosis is made. Complete data was obtained during the stay in the hospital from the time of diagnosis which includes the hospital stay. The onset of severe sepsis and septic shock were assessed during hospital stay. [b]RESULT:[/b] Out of the 100 patients, the incidence of sepsis was found to be high in the elderly age group. 39% are males and 61% are females. 50% had sepsis, 39% had severe sepsis, 11% had septic shock. The common organ dysfunction encountered were renal 50%, followed by hepatic (46%), CNS (2%) and respiratory (2%).The number of organ dysfunction in individual patients are none in 50(50%), 1 in 47(47%) and 2 in 3(3%). Out of 100 patients, 26(26%) had positive blood culture and 74(74%) had no organism grown in blood culture. According to grade of sepsis, patient with only sepsis had 100% recovery, while 92.31% of severe sepsis recovered, 7.69% expired and those with septic shock 72.3% recovered and 27.27% expired. [b]CONCLUSION[/b]: In this study we conclude that positive blood cultures were found in 26% of patients which are predominantly gram negative organisms. The common organ failure we encountered was renal. The common source of infection is respiratory tract followed by urinary tract. The prognosis was good in initial stages of sepsis, but was grave with septic shock (27.7% mortality). Hence early recognition and prompt management of sepsis is of paramount importance.
Authors and Affiliations
Prem Batham
Keywords
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- EP ID EP143509
- DOI 10.14260/jemds/2015/1402
- Views 86
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