The antiviral activity of leaves of Eucalyptus camaldulensis (Dehn) and Eucalyptus torelliana (R. Muell)
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 5
Abstract
Human enteroviruses are the major cause of aseptic meningitis and are resistant to all known antibiotics and chemotherapeutic agents. Methanolic extracts of Eucalyptus camaldulensis and Eucalyptus torelliana were tested on human enteroviruses: Poliovirus type I, Coxsackievirus B and Echovirus 6. The virucidal tests showed that the crude extracts were active on the test viruses: poliovirus type 1, coxsackievirus B and echovirus 6 giving a neutralization index of one log and above. The cytotoxicity assay of the crude extracts to L20B (a genetically engineered mouse cell line) and human rhabdomyo sarcoma (RD) cells showed that the extract of E. torelliana was more toxic than the extract of E. camaldulensis. The antiviral study showed that the extract of E. torelliana was more active than that of E. camaldulensis.
Authors and Affiliations
Bolanle Alake Adeniyi , Olayemi Oluseun Ayepola , Festus Doyin Adu
Keywords
Related Articles
- EP ID EP153524
- DOI -
- Views 93
- Downloads 0
[sup][/sup] In vitro dissolution and physicochemical characterizations of novel PVP-based solid dispersions containing valsartan prepared by a freeze-drying method
Valsartan (VAL) shows poor oral bioavailability mainly as a result of its low water solubility at low pH. This study is designed to investigate the dissolution properties and physicochemical characteristics of nove...
Development and in vitro characterization of mebendazole delayed release tablet for colonic drug delivery
Abstract: The main objective behind this study was to formulate delayed release colon targeted tablet of Mebendazole by using different polymers. The precompressional parameters of powder blend were studied. The we...
Traditional herbal healers “Hakims” use various plants of the Cholistan desert, Pakistan for treating a number of infectious and non-infectious diseases. However, there has never been a scientific validation of the...
Oil, protein, antioxidants and free radical scavenging activity of stone from wild olive trees (Olea europaea L.)
The wild olive trees or oleaster (var. sylvestris) and the cultivated olive trees (var. europaea) constitute the two botanical varieties of Olea europaea L. from Mediterranean. In this study, a partial chemical pro...
Phytochemical screening and acute toxicity evaluation of Telfairia occidentalis aqueous extracts on rats
The phytochemical composition and acute toxicity of Telfairia occidentalis aqueous extracts were investigated in this study. Phytochemical screening was carried out on the pulverized leaf, root, pod and stem sample...