The Effectiveness of Long Acting Amide Local Anesthetics In Surgical Removal of Lower 3rd Molars – A Systematic Review.
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 11
Abstract
: Background: “Local or regional anaesthesia may be defined as a regional loss of sensation to a painful stimulus as well as loss of all other sensations including temperature, pressure and touch etc resulting from a reversible interruption of peripheral conduction along a specific neural pathway” Malamed1 .Local anesthetics are chemicals that block nerve conduction in a specific, temporary and reversible manner, without affecting the patient’s consciousness. The molecule consists of two poles: a hydrophilic tertiary or secondary amino group and a lipophilic aromatic ring. According to the type of intermediate alkyl linkage between them, they are classified in ester-type anesthetics, with an amino-ester bond and whose prototype is procaine, and the amide-type with an amino-amide bond and whose prototype is lidocaine2 .The choice of anesthetic solution should be based on three main clinical considerations: anesthetic potency, latency (time to onset of anesthesia), and duration of the anesthetic effect.1,3,4,5. A number of local anesthetic agents are available that provide rapid onset of surgical anesthesia and adequate duration of anesthetic effect6 Vasoconstrictors have been added to local anesthetic solutions to increase the quality and duration of anesthesia, avoid excessive intraoperative bleeding, and decrease systemic toxicity.
Authors and Affiliations
Dr. Muhammed Anvar Sadath B. D. S, (M. D. S) , Prof. Dr. Ashok. K. Ramadorai. FDRCS(Edin),FFRCS(Ire)2.
Keywords
Related Articles
- EP ID EP136367
- DOI -
- Views 108
- Downloads 0
The pharmacological and therapeutic importance of Eucalyptus species grown in Iraq
Abstract:- Eucalyptus species grown in Iraq were included Eucalyptus bicolor (Syn: Eucalyptus largiflorens), Eucalyptus griffithsii, Eucalyptus camaldulensis (Syn: Eucalyptus rostrata) Eucalyptus incrassate, Eucalyptus t...
Assessment of Knowledge, Attitudes and Practices of Mothers in Jos North Regarding Immunization
ABSTRACT: Background: The knowledge of mothers on immunization- a public health intervention that has greatly reduced mortality and morbidity globally- is very vital as they play a great role in child care. Th...
A Review on Step-by-Step Analytical Method Validation
When analytical method is utilized to generate results about the characteristics of drug related samples it is essential that the results are trustworthy. They may be utilized as the basis for decisions relating t...
Review on Uro-Lithiasis Pathophysiology and Aesculapian Discussion
Nephroliths are a common trouble worldwide with substantial morbidities and economic costs. This review describes focusing on update about the Pathogenesis formation of renal stone epidemiology. The most common adventure...
Therapeutic importance of Hyoscyamus species grown in Iraq (Hyoscyamus albus, Hyoscyamus niger and Hyoscyamus reticulates)- A review
Hyoscyamus is one of the most important and largest genera of the family Solanaceae comprising about 84 genera and more than 3000 species. All Hyoscyamus species are rich sources of tropane alkaloids, mainly hyoscyamine...