Therapeutic importance of Hyoscyamus species grown in Iraq (Hyoscyamus albus, Hyoscyamus niger and Hyoscyamus reticulates)- A review
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 6
Abstract
Hyoscyamus is one of the most important and largest genera of the family Solanaceae comprising about 84 genera and more than 3000 species. All Hyoscyamus species are rich sources of tropane alkaloids, mainly hyoscyamine and scopolamine. The phytochemical analysis showed that Hyoscyamus species contained alkaloids, flavonoids, tannins, terpenes, saponins, carbohydrates, cardiac glycosides and anthraquinones. They exerted many pharmacological effects included anti-diabetic, antioxidant, anticancer, insecticidal, antiasthmatic, antiallergic, antidiarrhoeal, antisecretory, Ca2+ channel-blocking, hypotensive, cardioprotective, hepatoprotective, antihyperuricemic, Anti- Parkinsonian, anticonvulsant, antidepressant, in addition to anticholinergic effects of tropane alkaloids. The current review discussed the chemical constituents, pharmacological and toxicological effects of Hyoscyamus species grown in Iraq.
Authors and Affiliations
Prof Dr Ali Esmail Al-Snafi
Keywords
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