Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 1
Abstract
To simplify the principles of pharmacokinetics, we designed a single-compartment model with certain assumptions. Objectives of designing this model were to understand the basic principles of pharmacokinetics, to represent graphically the typical natural log concentration versus time curve for single-compartment model after (intravenous) dose, and to understand how to calculate the elimination half-life using graphical log concentration versus time curve as well as using a mathematical method.
Authors and Affiliations
Ashishkumar Zala, ND Kantharia, Aashal B Shah
Keywords
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- EP ID EP96164
- DOI 10.5455/njppp.2015.5.010820143
- Views 120
- Downloads 0
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