Nerve conduction studies in cases with long-term unintentional exposure to pesticide spraying
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 2
Abstract
Background: Farm workers experience many work-related hazards, including exposure to organophosphorus (OP) compounds during the process of pesticide spraying during their crop season. The recurrent unintentional exposure to OP compounds may lead to motor and sensory nerve neuropathies and also have some delayed neurological sequels. Aims and Objectives: The aims of this study were (1) to find out the toxic effects of OP compound on motor nerve conduction velocity (MNCV) and (2) to compare the MNCV, in selected peripheral nerve (median nerve) of affected population with the normal population. Materials and Methods: A cross-sectional analytical study was conducted by recruiting 60 individuals matched with height, weight, and occupation matched (control group 30 and study group 30). Participants were selected randomly from the outpatient Department of Medical College Hospital with age group between 20 and 40 years, and both sexes were included. The MNCVs were recorded using multichannel polyrite machine. Results: MNCVs were evaluated on median nerves of both the sides. MNCV was recorded on distal stimulation. Our findings show that the motor abnormalities nerve velocities in case of exposed population were significantly less as compared to the controls in tested median nerve. This indicates the presence of abnormalities such as neuropathy in these patients. Conclusion: There was an evidence of peripheral neuropathy to some extent in peripheral nerves as evident by slow MNCVs in median nerve of those farmers who were exposed to the OP pesticide spraying in the farms and its consequent absorption through skin, inhalation, or ingestion as compared to the normal individuals.
Authors and Affiliations
Sakshi Gawande, Shivaji Chalak, Ashish Banginwar, Kiran Avachar, Jagdish Powar, Prafulla Chandak
Keywords
Related Articles
- EP ID EP451652
- DOI 10.5455/njppp.2018.8.0831918082017
- Views 63
- Downloads 0
The use of reversibility percent in spirometric assessment of chronic obstructive pulmonary diseases for the detrimental effect of 3rd generation beta-blockers
Background: For clinicians who work in respiratory medicine, the use of beta-blockers (BBs) has, for a long time, posed a dilemma because of the potential risk of bronchospasm and neutralization of the effectiveness of β...
A cross-sectional survey on awareness of applied clinical physiology concepts among medical interns in a southern tertiary care institution
Background: In India, the preclinical subjects - anatomy, physiology and biochemistry are taught during the 1st year of medical curriculum, as per the norms of Medical Council of India. Physiology is one of the preclinic...
The clinical skills of emergency medical staff confronting trauma
Background: Today, the accidents and catastrophes causing trauma are one of the fundamental health needs of industrial world, and also a prevalent cause of mortality, especially in Iran. Thus, pre-hospital and emergency...
Study of blood pressure, pre-hypertension, and hypertension in medical students
Background: Hypertension (HTN) is a non-communicable disease of major public health problem, and pre-HTN in adolescents and young adults is an important risk factor for developing HTN in the future. By detecting pre-HTN...
Learning strategies in medical school: A holistic approach to physiology
Background: In medical college medical curriculum needs to be evaluated on a regular basis because students perception about the subjects should be known to the teachers. Assessment of medical students regarding the unde...