Necrotizing Fasciitis of the Extremities– A Clinical Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Necrotizing fasciitis is a rapidly progressive fulminant infection of the deep fascia and subcutaneous tissue commonly involving extremities, perineum, scrotum, penis, abdominal wall. It is associated with significant morbidity and mortality. Trauma is the most commonly identified etiology. Elderly and immunocompromised patients are the most affected. Early diagnosis and differentiation from other non-necrotising skin and soft tissue infections is needed because delay in surgical debridement leads to larger area of necrosis and higher chance of mortality. Diagnosis is dependent on clinical features like disproportionate pain, tenderness beyond skin involvement, systemic signs of toxicity like fever and tachycardia, erythema, edema, presence of bullae etc. We present our experience with 45 cases of necrotizing fasciitis of the extremities with respect to etiology and triggering factors, clinical presentation, laboratory findings and treatment outcomes in the rural Indian setting. This is a retrospective observational study conducted with the aim of analyzing the factors influencing morbidity and mortality of necrotizing fasciitis. Demographic data, presence of co-morbidities, time interval from onset of symptoms to surgical intervention, nature of organisms isolated, derangement of laboratory indicators like haemoglobin, total WBC count, blood urea, serum creatinine, sodium levels were collected and analysed for their influence on duration of hospital stay and area of skin necrosis that needed grafting. It was found that delay in presentation was associated with larger area of necrosis which was statistically significant. However no association was found between age, sex, site of involvement, presence of comorbidities, history of local application of an irritant and area of necrosis.
Authors and Affiliations
Dr K. Karthik Raja. M. S
Keywords
Related Articles
- EP ID EP507848
- DOI -
- Views 47
- Downloads 0
Prophylactic Efficiency of Oral Ephedrine in Preventing Hypotension Due to Spinal Anaesthesia for Caesarean Section
The commonest form of anaesthesia for caesarean section is spinal anaesthesia. It is associated with a fall in blood pressure with a comparable fall in uteroplacental blood flow. This leads to fetal hypoxia and acidosis....
Chronic Pancreatitis with Pancreatic Calculi in Odisha, Surgical Procedures- A Study of 100 Cases
Odisha is one of the capitals of Chronic Pancreatitis in India. The cause of chronic pancreatitis ranges from alcohol, smoking, hypercalcemia, idiopathic to autoimmune. Most of the patients with pancreatic calculi are ma...
Treatment Outcome of Triple Negative Breast Cancer- A Retrospective Study from Regional Cancer Centre Kashmir
Abstract
Study of Liver and Kidney Biochemical Variations in Patients with Various Morphological Types of Leukemia at a Tertiary Healthcare Hospital
Leukemias are malignant neoplasm of the haematopoietic stem cells, arising in the bone marrow that flood the circulating blood or other organs. The objective of this study was to find out the effect of leukemia on liver...
A Comparative Study of Ondansetron versus Ondansetron with Dexamethasone in Prevention of Postoperative Nausea and Vomiting (PONV) in Patients Undergoing Modified Radical Mastectomy with Axillary Node Dissection Under General Anaesthesia
Modified radical mastectomy surgeries used to have high incidence of nausea and vomiting. Ondansetron and Dexamethasone both used to prevent postoperative nausea and vomiting .We evaluated the efficacy of Dexamethasone i...