Nerve conduction study for early detection of leprosy
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 12
Abstract
Background: Patient with wrist-drop and foot-drop was biopsied for mononeuritis multiplex. Diagnosis leprosy, came surprising as it was eliminated. Thus prompted, did research on electrophysiology data of leprosy patients referred for nerve conduction studies (NCS) Some mononeuritis multiplex patients diagnosed as vasculitis, became neuritic leprosy and biopsy results were incorporated. Eliminated in 2005, leprosy is a public health challenge; due to high endemic areas with transmission, hidden cases, decreased case detection, administrative and political issues. Combining NCS with clinical examination detect cases & contacts early. NCS with nerve biopsy diagnoses pure neuritic leprosy before disability. Objectives: (1) Use of NCS to study nerve involvement in leprosy. (2) Assess use of NCS & biopsy in pure neuritic leprosy Study Design: Observational Methods: Stored data-clinical & NCS of 36 patients and nerve-biopsy of seven pure neuritic leprosy-were collected from Electrophysiology records. Results: Total 36 patients; abnormal NCS-34, nerve thickening-34. NCS was abnormal in 204 nerves; nerves thickened in 154. Six of 7 Neuritic &11 of 29 others had disability. Disability risk is more for neuritic leprosy (RR-2.0714; CI- 1.2213-3.5133. p = 0.02).
Authors and Affiliations
Beena Vasanthy, Vijayan Chandrathil Parameswaran Nair, Haris AA, Jacob George
Keywords
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