NEUROLOGICAL MANIFESTATIONS IN HIV PATIENTS- A HOSPITAL-BASED STUDY OF JAWAHARLAL NEHRU INSTITUTE OF MEDICAL SCIENCES (JNIMS), IMPHAL, MANIPUR
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 41
Abstract
BACKGROUND The nervous system is the most frequent and serious target of Human Immunodeficiency Virus (HIV) infection. All the levels of neuroaxis can be involved including the brain, meninges, spinal cord and peripheral nerve. Aims and Objective- Despite the high prevalence of the disease in our state Manipur, very limited study has been done to evaluate the neurological aspects of HIV/AIDS from this part of India. This study is done to characterise various neurological manifestations of HIV/AIDS. Setting and Design- This cross-sectional observational study was done over a period of 2 years from January 2014 to December 2015 at Jawaharlal Nehru Institute of Medical Sciences (JNIMS), Manipur. MATERIALS AND METHODS A total of 142 HIV positive patients of both genders, age > 18 years, who were admitted in hospital due to HIV related symptoms were examined for the presence of neurological dysfunction. A detailed history, physical examination and relevant investigations were carried out. RESULTS Out of the 142 patients, 45 were found to have neurological involvement (31.7%). Out of the 45 patients, 26 patients were male (57.8%) compared to 19 female (42.2%). Majority of patients were between 30 - 40 years of age. Tuberculous meningitis was the most common illness (35.6%) followed by cryptococcal meningitis (20%). Distal Sensory Polyneuropathy (DSPN) was the most common primary illness (13.3%). Fever (55.6%) and headache (53.3%) were the most common symptoms. CONCLUSION We found a high prevalence of neurological manifestation (31.7%) in this setting. Secondary opportunistic infection were more common than the primary CNS disease.
Authors and Affiliations
Bobi Singh M, Ratankumar Singh M
Keywords
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- EP ID EP214006
- DOI 10.14260/Jemds/2017/704
- Views 63
- Downloads 0
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