Neuropsychiatric manifestations associated with systemic lupus erythematosus: A case report and selective review of literature
Journal Title: Telangana Journal of Psychiatry - Year 2018, Vol 4, Issue 2
Abstract
Introduction Systemic lupus erythematosus SLE is an autoimmune condition affecting multiple organ systems including central nervous system Its aetiology lies in abnormal antibody formation and complement activation Neuropsychiatric manifestations are known to occur in patients with SLE and vary from psychosis depression anxiety to cognitive impairment Here we report a case of depression with psychotic symptoms and suicidal ideations associated with SLECase Summary We present the case of a 30yearold female who presented with irritability crying spells feeling of guilt referential and persecutory ideations along with suicidal ideations She was diagnosed with severe depression with psychotic symptoms associated with SLE She improved over a period of 6 weeks with Quetiapine 300mg along with symptomatic management of underlying medical conditionConclusions Depression with psychotic symptoms is not an uncommon presentation of SLE It needs comprehensive management and multidisciplinary approach Hence physician has to be sensitized regarding neuropsychiatric manifestations of SLE for improving the morbidity and mortality associated with underlying depressionKeywords SLEDepressionPsychosis
Authors and Affiliations
Hemendra Singh, Udayan Bhaumik
Keywords
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- EP ID EP491362
- DOI 10.18231/2455-8559.2018.0013
- Views 77
- Downloads 0
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Neuropsychiatric manifestations associated with systemic lupus erythematosus: A case report and selective review of literature
Introduction Systemic lupus erythematosus SLE is an autoimmune condition affecting multiple organ systems including central nervous system Its aetiology lies in abnormal antibody formation and complement activation Neuro...